2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. CS-1-103

CS-1-103 is a potent estrogen receptor (ER) inhibitor. CS-1-103 inhibits ER transcriptional activity with an EC50 of 0.36 μM by recruiting methyl-CpG binding domain protein 2 (MBD2), HDACs and the nucleosome remodeling and deacetylase (NuRD) complex. CS-1-103 can be used for breast and prostate cancer research.

For research use only. We do not sell to patients.

CS-1-103

CS-1-103 Chemical Structure

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CS-1-103 Related Antibodies

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

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Description

CS-1-103 is a potent estrogen receptor (ER) inhibitor. CS-1-103 inhibits ER transcriptional activity with an EC50 of 0.36 μM by recruiting methyl-CpG binding domain protein 2 (MBD2), HDACs and the nucleosome remodeling and deacetylase (NuRD) complex. CS-1-103 can be used for breast and prostate cancer research[1].

IC50 & Target[1]

ER

0.36 μM (EC50)

Molecular Weight

720.92

Formula

C41H48N6O4S
SMILES

OC1=CC=C2C(CCC3C2CC[C@@]4(C)C3CC/C4=N\OCC(NCCCCCCNC(C5=CC=CC(NC6=NC(C7=NC=CC=C7)=CS6)=C5)=O)=O)=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CS-1-103 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CS-1-103Estrogen Receptor/ERRestrogen receptorTranscriptional Regulation via Active Control of Epigenetic ReprogrammingMBD2NuRDbreastprostateInhibitorinhibitorinhibit

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