1. Natural Products
  2. Plants Alkaloids
  3. Apocynaceae Eupatorium triplinerve Vahl.
  4. Catharanthus roseus (L.) G. Don
  5. Catharine

Catharine is an alkaloid found in Catharanthus roseus and can be synthesized in a cell-free system derived from Catharanthus roseus.

For research use only. We do not sell to patients.

Catharine

Catharine Chemical Structure

CAS No. : 1355-31-3

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Description

Catharine is an alkaloid found in Catharanthus roseus and can be synthesized in a cell-free system derived from Catharanthus roseus[1].

Cellular Effect
Cell Line Type Value Description References
HL-60 IC50
56.2 μM
Compound: 99
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth incubated for 48 hrs by WST-1 assay
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth incubated for 48 hrs by WST-1 assay
[PMID: 36170798]
K562 IC50
56.2 μM
Compound: 99
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by WST-1 assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by WST-1 assay
[PMID: 36170798]
Molecular Weight

822.94

Formula

C46H54N4O10

CAS No.
SMILES

CC[C@]1([C@H]2OC(C)=O)[C@@]3([H])[C@](C(C4=C5)=CC([C@](C6=C(CCN7C=O)C8=CC=CC=C8N6)(CC(C/C(CC)=C\7)=O)C(OC)=O)=C5OC)(CCN3CC=C1)[C@](N4C)([H])[C@@]2(O)C(OC)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Catharine
Cat. No.:
HY-N15379
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