2. Apoptosis
  3. Apoptosis
  4. CALR ligand 1

CALR ligand 1 (Compound 2a) is a calreticulin (CALR) ligand. CALR ligand 1 shows antitumor activity against triple-negative breast cancer (TNBC) cells (IC50=0.1 μM). CALR ligand 1 induces intracellular calcium overloading and triggers apoptosis in TNBC cells. CALR ligand 1 is promising for research of TNBC .

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CALR ligand 1 Chemical Structure

CALR ligand 1 Chemical Structure

CAS No. : 3055854-78-6

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CALR ligand 1 Related Antibodies

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Description

CALR ligand 1 (Compound 2a) is a calreticulin (CALR) ligand. CALR ligand 1 shows antitumor activity against triple-negative breast cancer (TNBC) cells (IC50=0.1 μM). CALR ligand 1 induces intracellular calcium overloading and triggers apoptosis in TNBC cells. CALR ligand 1 is promising for research of TNBC [1].

Molecular Weight

392.86

Formula

C17H17ClN4O3S
CAS No.
SMILES

O=S(C1=CC=C(C2=CN=C3C(C(NC(CCl)=O)=NN3)=C2)C=C1)(C(C)C)=O
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Purity & Documentation
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CALR ligand 1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CALR ligand 13055854-78-6CALR ligand1CALR ligand-1ApoptosisCALRTNBCapoptosisInhibitorinhibitorinhibit

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