1. PROTAC Protein Tyrosine Kinase/RTK Immunology/Inflammation
  2. Ligands for Target Protein for PROTAC Btk IKZF Family
  3. BTK/IKZF1/3 ligand 1

BTK/IKZF1/3 ligand 1 is a BTK/IKZF1/3 PROTAC ligand. BTK/IKZF1/3 ligand 1 can be conjugated with E3 ligase Ligand (HY-41547) and linker to synthesize PROTAC BTK/IKZF1/3 Degrader-1 (HY-179077). PROTAC BTK/IKZF1/3 Degrader-1 can be used for cancer research.

For research use only. We do not sell to patients.

BTK/IKZF1/3 ligand 1

BTK/IKZF1/3 ligand 1 Chemical Structure

CAS No. : 1791402-90-8

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Description

BTK/IKZF1/3 ligand 1 is a BTK/IKZF1/3 PROTAC ligand. BTK/IKZF1/3 ligand 1 can be conjugated with E3 ligase Ligand (HY-41547) and linker to synthesize PROTAC BTK/IKZF1/3 Degrader-1 (HY-179077). PROTAC BTK/IKZF1/3 Degrader-1 can be used for cancer research[1].

IC50 & Target[1]

IKZF1

 

IKZF3

 

Molecular Weight

320.78

Formula

C14H17ClN6O

CAS No.
SMILES

CN1CCN(C1=O)[C@@H]2CCCN(C2)C3=CN=C(C(Cl)=N3)C#N

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
BTK/IKZF1/3 ligand 1
Cat. No.:
HY-179076
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