2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. AZD-2327

AZD-2327 is a potent and selective δ-opioid receptor agonist. AZD-2327 binds to the human opioid receptor (Ki = 0.49 and 0.75 nM and EC50 = 24 and 9.2 nM at the C27 and F27 isoforms, respectively). AZD-2327 shows selectivity of >1000-fold over the human μ- and κ-opioid receptor subtypes as well as >130 other receptors and channels. AZD-2327 exhibits antidepressant and anxiolytic activities and can be used for the research of neurological disease.

For research use only. We do not sell to patients.

AZD-2327

AZD-2327 Chemical Structure

CAS No. : 875647-81-7

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AZD-2327 Related Antibodies

Top Publications Citing Use of Products

View All Opioid Receptor Isoform Specific Products:

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μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

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Description

AZD-2327 is a potent and selective δ-opioid receptor agonist. AZD-2327 binds to the human opioid receptor (Ki = 0.49 and 0.75 nM and EC50 = 24 and 9.2 nM at the C27 and F27 isoforms, respectively). AZD-2327 shows selectivity of >1000-fold over the human μ- and κ-opioid receptor subtypes as well as >130 other receptors and channels. AZD-2327 exhibits antidepressant and anxiolytic activities and can be used for the research of neurological disease[1].

IC50 & Target[1]

δ Opioid Receptor/DOR

 

Molecular Weight

474.61

Formula

C29H35FN4O
CAS No.
SMILES

CCN(CC)C(C(C=C1)=CC=C1[C@H](C2=CC(N)=CC=C2)N3CCN(CC4=CC=C(F)C=C4)CC3)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AZD-2327 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AZD-2327875647-81-7AZD2327AZD 2327Opioid Receptorδ-opioid receptorκ-opioidμ-opioidantidepressantanxiolyticC27F27Inhibitorinhibitorinhibit

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