ZPR1 Antibody (YA6842)

Cat. No.: HY-P87149: Data Sheet User Guide for Antibodies
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ZPR1 Antibody (YA6842) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ZPR1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

ZPR1 Antibody (YA6842) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ZPR1.

Host

Rabbit

Clonality

Recombinant, Monoclonal

Molecular Weight

Predicted band size: 51 kDa

Species Reactivity

Human, Mouse

SwissProt ID

O75312

Gene ID

8882 [NCBI]

Immunogen

Recombinant protein within human ZPR1 aa 360-459/459.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:200
FC FC: Flow Cytometry	1:500-1:1000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Acts as a signaling molecule that communicates proliferative growth signals from the cytoplasm to the nucleus. It is involved in the positive regulation of cell cycle progression (PubMed:29851065). Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Cajal bodies. Induces neuron differentiation and stimulates axonal growth and formation of growth cone in spinal cord motor neurons. Plays a role in the splicing of ce

Subcellular Localization：Nucleus; Nucleus, nucleolus; Nucleus, gem; Nucleus, Cajal body; Cytoplasm, perinuclear region; Cytoplasm; Cell projection, axon; Cell projection, growth cone

Subunit：Component of an import snRNP complex composed of KPNB1, SNUPN, SMN1 and ZNF259. Interacts (via C-terminal region) with SMN1 (via C-terminal region); the interaction occurs after treatment with serum. Interacts with elongation factor 1-alpha EEF1A1; the interaction occurs in a epidermal growth factor (EGF)-dependent manner. Interacts (via zinc fingers) with EGFR (via C-terminal cytoplasmic kinase domain); the interaction is negatively regulated in response to epidermal growth factor (EGF) stimula

Synonyms

MGC110983 antibody; Zinc finger protein 259 antibody; Zinc finger protein ZPR1 antibody; ZNF 259 antibody; ZNF259 antibody; ZPR1 antibody; ZPR1_HUMAN antibody;

Documentation

User Guide for Antibodies (1077 KB)