2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. XRCC1 Antibody (YA5297)

XRCC1 Antibody (YA5297)

Cat. No.: HY-P85605
User Guide for Antibodies Technical Support

XRCC1 Antibody (YA5297) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to XRCC1.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

XRCC1 Antibody (YA5297) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to XRCC1.
Background

XRCC1 is a scaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes. It negatively regulates the ADP-ribosyltransferase activity of PARP1 during base-excision repair to prevent excessive PARP1 activity. XRCC1 recognizes and binds poly-ADP-ribose chains, specifically interacting with auto-poly-ADP-ribosylated PARP1 to limit its activity. by similar: These functions have been demonstrated in multiple studies, including the regulatory mechanisms of PARP1 activity.
Gene ID
SwissProt ID
Synonyms
DNA repair protein XRCC1; RCC; X ray repair complementing defective repair in chinese hamster; X ray repair complementing defective repair in chinese hamster cells 1; X ray Repair Complementing Defective Repair in Chinese Hamster Cells; X ray repair cross complementing protein 1; X ray repair, complementing defective, repair in Chinese hamster; X-ray repair cross-complementing protein 1; XRCC 1; Xrcc1; XRCC1_HUMAN.
Molecular Weight

Observed band size: 82 kDa
Purity

affinity chromatography.
Conjugation

Non-conjugated
Modification

Unmodified
Product Categories

Primary Antibody; Mouse Monoclonal Antibody
Clonality

Monoclonal
Host

Mouse
Reactivity

Human
Dilution Ratio

WB: 1:1000
Application

WB
Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Immunogen

Purified recombinant human XRCC1 protein fragments expressed in E.coli.
Documentation
User Guide for Antibodies (1077 KB)

XRCC1 Antibody (YA5297) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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XRCC1 Antibody (YA5297)
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