TRAF1 Antibody (YA6996)

Cat. No.: HY-P87313: Data Sheet User Guide for Antibodies
FAQs
Technical Support

TRAF1 Antibody (YA6996) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TRAF1.

For research use only. We do not sell to patients.

Size	Price	Stock
10 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

TRAF1 Antibody (YA6996) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TRAF1.

Host

Rabbit

Clonality

Recombinant, Monoclonal

Molecular Weight

Predicted band size: 46 kDa;

Observed band size: 50 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Rat

SwissProt ID

Q13077

Immunogen

Recombinant protein within human TRAF1 aa 1-200.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:10000
IP IP: Immunoprecipitation	1-2μg/sample

Sensitivity	Endogenous	Purity	Protein A affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2

Subunit：Homotrimer (PubMed:15383523, PubMed:20385093). Heterotrimer with TRAF2 (PubMed:19287455, PubMed:20385093, PubMed:8069916). Interacts with TNFRSF1A/TNFR1, TNFRSF1B/TNFR2, TNFRSF4, TNFRSF5/CD40, TNFRSF8/CD30, TNFRSF9/CD137, TNFRSF11A/RANK, TNFRSF13C, TNFRSF18/AITR, TNFRSF17/BCMA, TNFRSF19/TROY, TNFRSF19L/RELT, XEDAR, EDAR, Epstein-Barr virus BNFL1/LMP-1, TANK/ITRAF, TRAIP and RIPK2 (PubMed:10037686, PubMed:10809768, PubMed:10903733, PubMed:11035039, PubMed:11313261, PubMed:16323247, PubMed:1928745

Synonyms

4732496E14Rik antibody; EBI6 antibody; EBV induced protein 6 antibody; Epstein-Barr virus-induced protein 6 antibody; MGC:10353 antibody; Tnf receptor associated factor 1 antibody; TNF receptor-associated factor 1 antibody; TRAF 1 antibody; TRAF1 antibody; TRAF1_HUMAN antibody

Documentation

User Guide for Antibodies (1077 KB)