1. Antibodies
  2. Primary Antibodies
  3. Monoclonal Antibodies
  4. Thioredoxin Antibody (YA4612)

Thioredoxin Antibody (YA4612)

Cat. No.: HY-P84915
User Guide for Antibodies Technical Support

Thioredoxin Antibody (YA4612) is a mouse-derived and non-conjugated IgG1 antibody, targeting to Thioredoxin (TRX). It can be applicated for WB, ELISA assays.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Thioredoxin Antibody (YA4612) is a mouse-derived and non-conjugated IgG1 antibody, targeting to Thioredoxin (TRX). It can be applicated for WB, ELISA assays.

Background

Thioredoxin is a protein involved in various redox reactions via the reversible oxidation of its active center dithiol to a disulfide, catalyzing dithiol-disulfide exchange reactions. It plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, contributing to the cellular response to nitric oxide (NO)—for instance, by nitrosylating the active site Cys of CASP3 to inhibit caspase-3 activity (similar function: ADF enhances the expression of the interleukin-2 receptor TAC). Additionally, Thioredoxin induces FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its redox status and stimulates AP-1 transcriptional activity.

Gene ID
SwissProt ID
Synonyms
Thioredoxin
Molecular Weight

Predicted band size: 12 kDa; Observed band size: 12 kDa

Purity

affinity purified.

Conjugation

Non-conjugated

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Host

Mouse

Reactivity

Tag

Dilution Ratio

WB: 1/500-1/2000; IHC: 1/100-1/1000; IF: 1/100-1/200; FC: 1/200-1/400; ELISA: 1/10000

Application

WB, ELISA

Appearance

Liquid

Formulation

Supplied in ascitic fluid containing 0.03% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG1

Immunogen

Purified recombinant fusion protein with Thioredoxin (TRX) tag.

Documentation

Thioredoxin Antibody (YA4612) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Thioredoxin Antibody (YA4612)
Cat. No.:
HY-P84915
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