TCP-1 β Antibody (YA5077)

TCP-1 β Antibody (YA5077) is a mouse-derived and non-conjugated monoclonal antibody, targeting to TCP-1 β. It can be applicated for WB, ICC/IF, FC, ELISA assays, in the background of human, mouse, rat, monkey.

CCT2 operates as an integral component of the chaperonin-containing T-complex (TRiC), a sophisticated molecular chaperone complex pivotal for protein folding through ATP hydrolysis. This versatile complex plays a crucial role in mediating the folding of various proteins, including WRAP53/TCAB1, thus influencing telomere maintenance. Furthermore, as part of the TRiC complex, CCT2 may contribute to the assembly of the BBSome, a complex essential for ciliogenesis that regulates the transport of vesicles to cilia. The TRiC complex's involvement in the folding of actin and tubulin underscores its multifaceted functions in cellular processes (Probable). Structurally, CCT2 is a key constituent of the TRiC complex, a heterooligomeric assembly characterized by two stacked rings, each measuring 12 to 16 nm in diameter. Beyond its structural role, CCT2 engages in interactions with various proteins, including PACRG, FLCN, and DLEC1, further highlighting its significance in diverse cellular processes.

P78371

Predicted band size: 57 kDa;

affinity purified.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human, Mouse, Rat, Monkey

WB: 1:500-1:2000; ICC/IF: 1:200-1:1000; FC: 1:200-1:400; ELISA: 1:10000

WB, ICC/IF, FC, ELISA

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

Purified recombinant fragment of human TCP-1 β expressed in E. Coli.