1. Antibodies
  2. Primary Antibodies
  3. Monoclonal Antibodies
  4. SOX10 Antibody (YA4110)

SOX10 Antibody (YA4110)

Cat. No.: HY-P84413
User Guide for Antibodies Technical Support

SOX10 Antibody (YA4110) is a mouse-derived and non-conjugated IgG1 antibody, targeting to SOX10. It can be applicated for IHC-P, ELISA assays, in the background of human.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

SOX10 Antibody (YA4110) is a mouse-derived and non-conjugated IgG1 antibody, targeting to SOX10. It can be applicated for IHC-P, ELISA assays, in the background of human.

Background

SOX10 is a transcription factor that plays a central role in developing and mature glia (By similarity). It specifically activates the expression of myelin genes, such as DUSP15 and MYRF, during oligodendrocyte (OL) maturation, thereby playing a key role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). It acts as a transcriptional activator of MITF, synergistically with PAX3 (PubMed:21965087). Additionally, it transcriptionally activates MBP by binding to the gene promoter (By similarity).

Gene ID
SwissProt ID
Synonyms
DOM; WS4; PCWH; WS2E; WS4C
Molecular Weight

Predicted band size: 49 kDa; Observed band size: 60-80 kDa

Purity

affinity purified.

Conjugation

Non-conjugated

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Host

Mouse

Reactivity

Human

Dilution Ratio

IHC: 1/200-1/1000; ELISA: 1/10000

Application

IHC-P, ELISA

Appearance

Liquid

Formulation

Supplied in PBS with 0.05% sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG1

Immunogen

Purified recombinant fragment of human SOX10 (AA: 147-252) expressed in E. Coli.

Documentation

SOX10 Antibody (YA4110) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
SOX10 Antibody (YA4110)
Cat. No.:
HY-P84413
Quantity:
MCE Japan Authorized Agent: