SLC22A12 Antibody (YA4439)

SLC22A12 Antibody (YA4439) is a mouse-derived and non-conjugated IgG1 antibody, targeting to SLC22A12. It can be applicated for WB, IHC-P, FC, ELISA assays, in the background of human, mouse.

SLC22A12 is an electroneutral antiporter that translocates urate across the apical membrane of proximal tubular cells in exchange for monovalent organic or inorganic anions. It is involved in the renal reabsorption of urate and helps maintain blood levels of uric acid. This protein mediates urate uptake by exchanging with organic anions such as (S)-lactate and nicotinate, as well as inorganic anion Cl(-). Other inorganic anions like Br(-), I(-), and NO3(-) may also act as counteranions for urate exchange. Additionally, SLC22A12 mediates orotate tubular uptake coupled with nicotinate efflux and, to a lesser extent, lactate efflux, suggesting a potential role in orotate renal reabsorption. Orotate transport is Cl(-)-dependent. by similar

Q96S37

Predicted band size: 60 kDa; Observed band size: 60 kDa

affinity purified.

Non-conjugated

Primary Antibody; Mouse Monoclonal Antibody

Mouse

Human, Mouse

WB: 1/500-1/2000; IHC: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000

WB, IHC-P, FC, ELISA

Liquid

Supplied in PBS with 0.05% sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Purified recombinant fragment of human SLC22A12 (AA: 30-145) expressed in E. Coli.