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  4. RBBP4 Antibody (YA103)

RBBP4 Antibody (YA103)

Cat. No.: HY-P80301
User Guide for Antibodies Technical Support

RBBP4 Antibody (YA103) is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to RbAP48. It can be used for WB,ICC,IHC-P,FC,IP assays with tag free, in the background of Human, Mouse, Rat.

For research use only. We do not sell to patients.

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

RBBP4 Antibody (YA103) is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to RbAP48. It can be used for WB,ICC,IHC-P,FC,IP assays with tag free, in the background of Human, Mouse, Rat.

Background

RbAP48 is a core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors, and histone deacetylases (HDACs) to their histone substrates in a nucleosomal DNA-regulated manner. It is a component of the chromatin assembly factor 1 (CAF-1) complex, which is involved in chromatin assembly following DNA replication and repair. RbAP48 is also part of the core histone deacetylase (HDAC) complex, promoting histone deacetylation and transcriptional repression. Additionally, it participates in the nucleosome remodeling and histone deacetylase (NuRD) complex, facilitating transcriptional repression through histone deacetylation and nucleosome remodeling. RbAP48 is also a component of the PRC2 complex, which represses homeotic genes during development, and the NURF (nucleosome remodeling factor) complex.

Tag

Free

Gene ID
SwissProt ID
Molecular Weight

Predicted band size: 48 kDa; Observed band size: 48 kDa

Purity

Protein A affinity purified.

Subcellular Location

Nucleus.

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Epigenetics and Nuclear Signaling

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

Dilution Ratio

WB: 1:500-1:2,000 ;ICC: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IP:1:10-1:50

Application

WB, ICC/IF, IHC-P, FC, IP

Appearance

Liquid

Formulation

Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

Synthetic peptide corresponding to Human RbAP48.AA range:1-98.

Database
Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
RBBP4 Antibody (YA103)
Cat. No.:
HY-P80301
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