Rab1A Antibody (YA6750)

Cat. No.: HY-P87057: Data Sheet User Guide for Antibodies
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Rab1A Antibody (YA6750) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Rab1A.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Rab1A Antibody (YA6750) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Rab1A.

Host

Rabbit

Clonality

Recombinant, Monoclonal

Molecular Weight

Predicted band size: 23 kDa;

Observed band size: 23 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P62820

Gene ID

5861 [NCBI]

Immunogen

Synthetic peptide within human Rab1A aa 156-205 / 205.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-1:200
FC FC: Flow Cytometry	1:1000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (PubMed:20639577, PubMed:20861236, PubMed:21303926, PubMed:22939626). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (PubMed:20639577, PubMed:20861236, PubMed:21303926,

Subcellular Localization：Golgi apparatus; Endoplasmic reticulum; Early endosome; Cytoplasm, cytosol; Membrane; Melanosome

Subunit：May interact with YIPF5 (By similarity). Interacts with C9orf72; the interaction mediates recruitment of RAB1A to the ATG1/ULK1 kinase complex (PubMed:27334615). Interacts with GDI1; this promotes dissociation from membranes (PubMed:20176951, PubMed:23815289)

Synonyms

GTP binding protein RAB 1A antibody; mKIAA3012 antibody; RAB 1 antibody; Rab 1A antibody; RAB1 antibody; RAB1, member RAS oncogene family antibody; Rab1A antibody; RAB1A member RAS oncogene family antibody; RAB1A_HUMAN antibody; Ras related protein Rab 1A antibody; GTP binding protein RAB 1A antibody; mKIAA3012 antibody; RAB 1 antibody; Rab 1A antibody; RAB1 antibody; RAB1, member RAS oncogene family antibody; Rab1A antibody; RAB1A member RAS oncogene family antibody; RAB1A_HUMAN antibody; Ras related protein Rab 1A antibody; Ras-associated protein RAB1 antibody; Ras-related protein Rab-1A antibody; YPT1 antibody; YPT1 related protein antibody; YPT1-related protein antibody;

Documentation

User Guide for Antibodies (1077 KB)