PPAR alpha Antibody (YA6141)

PPAR alpha Antibody (YA6141) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PPAR α. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

PPAR α is a ligand-activated transcription factor and a key regulator of lipid metabolism. It is activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC) and by oleylethanolamide, a naturally occurring lipid that regulates satiety. As a receptor for peroxisome proliferators, such as hypolipidemic drugs and fatty acids, PPAR α regulates the peroxisomal beta-oxidation pathway of fatty acids. It functions as a transcription activator for the ACOX1 and P450 genes, with its transactivation activity requiring heterodimerization with RXRA and being antagonized by NR2C2. PPAR α may also be involved in propagating clock information to metabolic pathways regulated by PER2.

Q07869

Predicted band size: 52 kDa; Observed band size: 52 kDa

Protein A

Non-conjugated

Unmodified

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Monoclonal

Rabbit

Human, Mouse, Rat

WB: 1:1000-1:5000; ELISA: 1:5000-1:20000; IP: 1:50-1:200

WB, IP, ELISA

Liquid

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG