**Mono-Methyl Arginine (R*GG) Antibody (YA6663)**

Cat. No.: HY-P86970: Data Sheet User Guide for Antibodies
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Mono-Methyl Arginine (R*GG) Antibody (YA6663) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mono-Methyl Arginine (R*GG).

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Mono-Methyl Arginine (R*GG) Antibody (YA6663) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mono-Methyl Arginine (R*GG).

Host

Rabbit

Clonality

Recombinant, Monoclonal

Molecular Weight

Observed band size: Mutiple kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Species independent

SwissProt ID

Q63009

Gene ID

60421 [NCBI]

Immunogen

Synthetic mono-methyl arginine peptide library containing R*GG motifs.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:5000

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, FMR1, ILF3, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15, EWS, HABP4, SERBP1, RBM15, FOXO1, CHTOP, MAP3K5/ASK1 and MICU1 (PubMed:12737817, PubMed:15837430, PubMed:18492485, PubMed:19405910, PubMed:22095282). Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-3' (H4R3me

Subcellular Localization：Nucleus; Nucleus, nucleoplasm; Cytoplasm, cytosol; Cytoplasm; Lysosome membrane

Subunit：Homodimer and heterodimer with PRMT8. Homooctamer; individual homodimers associates to form a homooctamer. Interacts with NFATC2IP. Interacts with ILF3 and SUPT5H. Individual homodimers can associate to form a homohexamer. Interacts with FOXO1; the interaction methylates FOXO1, retaining it in the nucleus and increasing its transcriptional activity. Methylation of FOXO1 is increased with oxidative stress. Interacts with CHTOP; the interaction methylates CHTOP, enabling its interaction with the 5

Synonyms

Arginine (mono methyl) antibody; Mono-Methyl Arginine (R*GG)

Documentation

User Guide for Antibodies (1077 KB)