MDMX Antibody (YA4964)

MDMX Antibody (YA4964) is a mouse-derived and non-conjugated monoclonal antibody, targeting to MDMX. It can be applicated for WB, IHC-P, ICC/IF, ELISA assays, in the background of human.

MDMX, along with MDM2, is involved in the regulation of TP53. It inhibits cell cycle arrest and apoptosis by binding to the transcriptional activation domains of p53/TP53 and TP73/p73. MDMX also inhibits the degradation of MDM2 and can reverse MDM2-mediated degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. by similar: These functions are analogous to those of MDM2.

O15151

Predicted band size: 55 kDa;

affinity purified.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human

WB: 1:500-1:2000; IHC: 1:200-1:1000; ICC/IF: 1:200-1:1000; ELISA: 1:10000

WB, IHC-P, ICC/IF, ELISA

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

Purified recombinant fragment of human MDMX expressed in E. Coli.