2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. KMT2D Antibody (YA3502)

KMT2D Antibody (YA3502)

Cat. No.: HY-P83805
User Guide for Antibodies Technical Support

KMT2D Antibody (YA3502) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to KMT2D.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

KMT2D Antibody (YA3502) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to KMT2D.
Background

KMT2D Protein, a histone methyltransferase, orchestrates the transfer of methyl groups from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' on histone H3 (H3K4). Integral to the chromatin remodeling machinery, it predominantly establishes H3K4me1 methylation marks at active chromatin sites associated with transcription and DNA repair processes. Functioning as a coactivator for the estrogen receptor, KMT2D is recruited by ESR1, thereby activating transcription. The enzyme's activity in depositing specific histone marks at functionally relevant genomic locations underscores its crucial role in modulating chromatin structure and gene expression.
Gene ID
SwissProt ID
Synonyms
ALR; KMS; MLL2; MLL4; AAD10; KABUK1; TNRC21; CAGL114
Molecular Weight

Predicted band size: 593 kDa; Observed band size: 22 kDa
Purity

affinity purified.
Conjugation

Non-conjugated
Product Categories

Primary Antibody; Mouse Monoclonal Antibody
Clonality

Monoclonal Antibody
Host

Mouse
Reactivity

Human
Dilution Ratio

IHC: 1:200-1:1000; FC: 1:200-1:400; ELISA: 1:10000
Application

IHC-P, FC, ELISA
Appearance

Liquid
Formulation

Supplied in PBS with 0.05% sodium azide
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG2b
Immunogen

Purified recombinant fragment of human KMT2D (AA: 445-599) expressed in E. Coli.
Documentation
User Guide for Antibodies (1077 KB)

KMT2D Antibody (YA3502) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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KMT2D Antibody (YA3502)
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HY-P83805
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