Junctophilin-2 Antibody (YA6621)

Cat. No.: HY-P86928: Data Sheet COA
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User Guide for Antibodies
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Junctophilin-2 Antibody (YA6621) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Junctophilin-2.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Junctophilin-2 Antibody (YA6621) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Junctophilin-2.

Host

Mouse

Clonality

Recombinant, Monoclonal

Molecular Weight

Predicted band size: 74 kDa;

Observed band size: 70 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9BR39

Gene ID

57158 [NCBI]

Immunogen

Synthetic peptide within Human Junctophilin-2 aa 1-50 / 696.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:1000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Membrane-binding protein that provides a structural bridge between the plasma membrane and the sarcoplasmic reticulum and is required for normal excitation-contraction coupling in cardiomyocytes (PubMed:20095964). Provides a structural foundation for functional cross-talk between the cell surface and intracellular Ca(2+) release channels by maintaining the 12-15 nm gap between the sarcolemma and the sarcoplasmic reticulum membranes in the cardiac dyads (By similarity). Necessary for proper intra

Subcellular Localization：Cell membrane; Peripheral membrane protein; Sarcoplasmic reticulum membrane; Single-pass type IV membrane protein; Endoplasmic reticulum membrane; Single-pass type IV membrane protein; Nucleus

Subunit：Interacts with TRPC3 (PubMed:20095964). Interacts with BAG5 and HSPA8; the interaction with HSPA8 is increased in the presence of BAG5 (PubMed:35044787)

Synonyms

FLJ40969 antibody; JP-2 antibody; JP2 antibody; Jph2 antibody; JPH2_HUMAN antibody; Junctophilin 2 antibody; Junctophilin type 2 antibody; Junctophilin-2 antibody; OTTHUMP00000031651 antibody; OTTHUMP00000031652 antibody;

Documentation

Select Batch:

Data Sheet (231 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)