FUNDC1 Antibody (YA6574)

Cat. No.: HY-P86881: Data Sheet User Guide for Antibodies
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FUNDC1 Antibody (YA6574) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FUNDC1.

For research use only. We do not sell to patients.

Size	Price	Stock
10 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

FUNDC1 Antibody (YA6574) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FUNDC1.

Host

Rabbit

Clonality

Recombinant, Monoclonal

Molecular Weight

Predicted band size: 17 kDa;

Observed band size: 17 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Rat

SwissProt ID

Q8IVP5

Gene ID

139341 [NCBI]

Immunogen

Recombinant protein within N terminal human FUNDC1.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Integral mitochondrial outer-membrane protein that mediates the formation of mitochondria-associated endoplasmic reticulum membranes (MAMs) (PubMed:33972548). In turn, mediates angiogenesis and neoangiogenesis through interference with intracellular Ca(2+) communication and regulation of the vascular endothelial growth factor receptor KDR/VEGFR2 expression at both mRNA and protein levels (PubMed:33972548). Also acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitocho

Subcellular Localization：Mitochondrion outer membrane; Multi-pass membrane protein

Subunit：Interacts (via YXXL motif) with MAP1 LC3 family proteins MAP1LC3A, MAP1LC3B and GABARAP. Interacts with DNM1L/DPR1 (PubMed:27145933). Interacts with GPX4 (PubMed:36828120)

Synonyms

FUN14 domain containing 1 antibody; FUN14 domain containing protein 1 antibody; FUN14 domain-containing protein 1 antibody; FUND1_HUMAN antibody; fundc1 antibody;

Documentation

User Guide for Antibodies (1077 KB)