Fes Antibody (YA4851)

Fes Antibody (YA4851) is a mouse-derived and non-conjugated monoclonal antibody, targeting to Fes. It can be applicated for WB, IHC-P, ICC/IF, ELISA assays, in the background of human.

FES, a tyrosine-protein kinase, functions downstream of cell surface receptors, contributing to the regulation of various cellular processes, including the actin cytoskeleton dynamics, microtubule assembly, cell attachment, and cell spreading. It plays a crucial role in FCER1-mediated signaling in mast cells, influencing mast cell degranulation, and acts downstream of the KIT receptor. Additionally, FES is involved in cell differentiation, promoting neurite outgrowth in response to NGF signaling. It contributes to cell scattering and migration triggered by HGF-induced activation of EZR. FES phosphorylates key proteins such as BCR, leading to the down-regulation of BCR kinase activity, as well as HCLS1/HS1, PECAM1, STAT3, and TRIM28, underscoring its diverse regulatory functions in cellular signaling pathways.

P07332

Predicted band size: 93 kDa;

affinity purified.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human

WB: 1:500-1:2000; IHC: 1:200-1:1000; ELISA: 1:10000; ICC/IF: 1:50-200

WB, IHC-P, ICC/IF, ELISA

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

Purified recombinant fragment of Fer expressed in E. Coli.