2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. EGR2 Antibody (YA1926)

EGR2 Antibody (YA1926)

Cat. No.: HY-P82181
User Guide for Antibodies Technical Support

EGR2 Antibody (YA1926) is a non-conjugated IgG antibody, targeting EGR2, with a predicted molecular weight of 50 kDa (observed band size: 53 kDa). EGR2 Antibody (YA1926) can be used for WB experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.
or Bulk Inquiry

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

EGR2 Antibody (YA1926) is a non-conjugated IgG antibody, targeting EGR2, with a predicted molecular weight of 50 kDa (observed band size: 53 kDa). EGR2 Antibody (YA1926) can be used for WB experiment in human, mouse, rat background.
Background

EGR2 is a sequence-specific DNA-binding transcription factor involved in hindbrain segmentation and Schwann cell myelination. It regulates the expression of a subset of homeobox-containing genes (e.g., HOXA4, HOXB3, and HOXB2) to specify odd and even rhombomeres in the hindbrain (By similarity). EGR2 binds to two EGR2-consensus sites, EGR2A (5'-CTGTAGGAG-3') and EGR2B (5'-ATGTAGGTG-3'), in the HOXB3 enhancer to promote HOXB3 transcriptional activation (By similarity). It also binds specific DNA sites in the promoter regions of HOXA4, HOXB2, and ERBB2 (By similarity). In the peripheral nervous system, EGR2 regulates myelination by controlling the expression of myelin proteins (e.g., MPZ) and promoting Schwann cell differentiation (By similarity). Additionally, EGR2 may play a role in the innervation of jaw-opening musculature via trigeminal motor neurons (By similarity) and potentially in adipogenesis by regulating CEBPB expression (By similarity). EGR2 also functions as an E3 SUMO-protein ligase, facilitating SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation downregulates EGR2 transcriptional activity.
Gene ID
SwissProt ID
Synonyms
EGR2; KROX20; E3 SUMO-protein ligase EGR2; AT591; E3 SUMO-protein transferase ERG2 Curated; Early growth response protein 2 (EGR-2); Zinc finger protein Krox-20;
Molecular Weight

Predicted band size: 50 kDa; Observed band size: 53 kDa
Purity

Affinity Chromatography
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Epigenetics and Nuclear Signaling
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse, Rat
Dilution Ratio

WB: 1/500-1/1000
Application

WB
Appearance

Liquid
Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthesized peptide derived from human EGR2
Database

Entrez Gene: 1959 Human ; 13654 Mouse ;

SwissProt: P11161 Human ; P08152 Mouse ; A1XSY8Pig

OMIM: 605253 Human

Documentation
User Guide for Antibodies (1077 KB)

EGR2 Antibody (YA1926) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
EGR2 Antibody (YA1926)
Cat. No.:
HY-P82181
Quantity:
MCE Japan Authorized Agent:

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Country or Region *

Email Address *

     

Phone Number *

 

Organization Name *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.