Desmoglein 3 Antibody (YA1215)

Desmoglein 3 Antibody (YA1215) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1215), targeting Desmoglein 3. Desmoglein 3 Antibody (YA1215) can be used for IHC-P experiment in human background.

Desmoglein-3 (DSG3) is an integral component of intercellular desmosome junctions, playing a crucial role in mediating cell-cell adhesion. Functioning within these junctions, DSG3 is involved in the interaction between plaque proteins and intermediate filaments, contributing to the structural integrity and stability of tissues. Notably, DSG3 interacts with Plakophilin-2 (PKP2), emphasizing its role in coordinating the assembly and maintenance of desmosomal complexes. This interaction further highlights the intricate molecular network involved in cell-cell adhesion and reinforces the importance of DSG3 in ensuring the proper function and structural cohesion of tissues through its engagement in desmosomal signaling pathways. (

P32926

Predicted band size: 108 kDa; Observed band size: 145 kDa

Affinity Purified

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

IHC: 1/100-1/200

IHC-P

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.127.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

Recombinant protein of human Desmoglein 3