Cdc25B Antibody (YA520)

Cdc25B Antibody (YA520) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cdc25B.

CDC25B Protein, a member of the CDC25 family of phosphatases, plays a crucial role in cell cycle regulation by activating the cyclin-dependent kinase CDC2, facilitating entry into mitosis. With nuclear localization and export signals, CDC25B shuttles between the nucleus and cytoplasm, exhibiting nuclear presence during the M and G1 phases and cytoplasmic localization in S and G2 phases of the cell cycle. Despite its association with oncogenic properties, the precise role of CDC25B in tumor formation remains undetermined. The gene displays ubiquitous expression, with notable levels in lymph node (RPKM 21.4), appendix (RPKM 15.3), and 24 other tissues, underscoring its involvement in diverse cellular processes across various organs.

Free

P30305

Predicted band size: 65kDa; Observed band size: 64kDa

affinity purified by Protein A

Cytoplasm, Cytoskeleton.

Non-conjugated

Unmodified

Primary Antibody; Monoclonal Antibody

Monoclonal, Recombinant

Rabbit

Human

WB: 1:500-2000; FC: 1:50-100; IP: 1:20-50;

WB, FC, IP

Liquid

Supplied in10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human CDC25B. The exact sequence is proprietary to MCE.