C1QB Antibody (YA1634)

C1QB Antibody (YA1634) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1634), targeting C1QB, with a predicted molecular weight of 27 kDa (observed band size: 27 kDa). C1QB Antibody (YA1634) can be used for WB, IHC-P, ICC/IF experiment in human background.

C1QB protein plays a crucial role in the formation of C1, the initial component of the serum complement system. C1q associates with the proenzymes C1r and C1s, resulting in the assembly of C1. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 occurs upon engagement of the globular heads of C1q with the Fc regions of IgG or IgM antibodies within immune complexes. C1, in its active form, constitutes a calcium-dependent trimolecular complex composed of C1q, C1r, and C1s in a molar ratio of 1:2:2. The C1q subcomponent consists of nine subunits, with six being disulfide-linked dimers of the A and B chains, and the remaining three forming disulfide-linked dimers of the C chain.

P02746

Predicted band size: 27 kDa; Observed band size: 27 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Neuroscience

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200

WB, IHC-P, ICC/IF

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human C1QB