CEBP beta Antibody (YA576)

Cat. No.: HY-P80490: Data Sheet COA
SDS
User Guide for Antibodies
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Technical Support

CEBP beta Antibody (YA576) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CEBP beta.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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CEBP beta Antibody (YA576) Featured Recommendations:

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

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Description	CEBP beta Antibody (YA576) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CEBP beta.
Background	C/EBP Beta is a key transcription factor regulating genes involved in immune and inflammatory responses. It plays significant roles in adipogenesis, gluconeogenesis, liver regeneration, and hematopoiesis, with a consensus recognition site of 5'-T[TG]NNGNAA[TG]-3'. Its activity is modulated by protein interactions and post-translational modifications. During early embryogenesis, it shares redundant functions with CEBPA, promoting mitosis in hepatocytes and adipocytes while inhibiting T-cell proliferation by repressing MYC, thereby aiding T-helper 2 lineage differentiation. It binds regulatory regions of acute-phase and cytokine genes, influencing acute-phase reactions and inflammation. By similarity, it contributes to intracellular bacterial killing. In adipogenesis, it is rapidly expressed and, upon phosphorylation, induces CEBPA and PPARG to activate adipocyte phenotype-related genes. It is critical for ovarian follicle development (By similarity) and restricts osteoclastogenesis by repressing DSPP during odontoblast differentiation (By similarity). Essential for macrophage activation, it also drives immune responses like CD4(+) T-cell activation, granuloma formation, and endotoxin shock.
Tag	Free
Gene ID	1051 [NCBI]
SwissProt ID	P17676
Molecular Weight	Predicted band size: 36 kDa; Observed band size: 36 kDa
Purity	Protein A affinity purified.
Subcellular Location	Cytoplasm, Nucleus.
Conjugation	Non-conjugated
Modification	Unmodified
RRID	AB_3102563
Research Field	Epigenetics and Nuclear Signaling
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human, Rat
Dilution Ratio	WB: 1:500-1:2,000 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.
Application	WB, FC, IP
Appearance	Liquid
Formulation	Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	Synthetic peptide corresponding to Rat C/EBP Beta.AA range:248-297.
Database	Entrez Gene: 1051 Human ; 12608 Mouse ; 24253 Rat SwissProt: P17676 Human ; P28033 Mouse ; P21272 Rat OMIM: 189965 Human
Documentation	Select Batch: Data Sheet (235 KB) SDS (251 KB) COA (191 KB) User Guide for Antibodies (1077 KB)

CEBP beta Antibody (YA576) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CEBP beta Antibody (YA576)

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CEBP beta Antibody (YA576) Related Classifications

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