2. Immunology/Inflammation
  3. Interleukin Related
  4. Anti-Mouse IL-25 Antibody (2C3)

Anti-Mouse IL-25 Antibody (2C3) 

Cat. No.: HY-P990216 Purity: 95.00%
COA
SDS
Technical Support

Anti-Mouse IL-25 Antibody (2C3) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to mouse IL-25. Anti-Mouse IL-25 Antibody (2C3) can neutralize IL-25. Anti-Mouse IL-25 Antibody (2C3) can be used for inflammation researches, such as colitis and asthma.

For research use only. We do not sell to patients.

Anti-Mouse IL-25 Antibody (2C3)

Anti-Mouse IL-25 Antibody (2C3) Chemical Structure

Size Price Stock Quantity
1 mg In-stock
5 mg In-stock
10 mg In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Anti-Mouse IL-25 Antibody (2C3) Featured Recommendations:

Anti-Mouse IL-25 Antibody (2C3) Related Antibodies

Top Publications Citing Use of Products

View All Interleukin Related Isoform Specific Products:

View All Isoforms
IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Anti-Mouse IL-25 Antibody (2C3) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to mouse IL-25. Anti-Mouse IL-25 Antibody (2C3) can neutralize IL-25. Anti-Mouse IL-25 Antibody (2C3) can be used for inflammation researches, such as colitis and asthma[1][2][3].

Isotype

Mouse IgG1 kappa
Recommend Isotype Controls
Species Reactivity

Mouse
IC50 & Target

IL-25
In Vitro

Anti-Mouse IL-25 Antibody (2C3) (1 μg/mL, 72 h) inhibits IL-13 production in nuocyte cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Mouse IL-25 Antibody (2C3) Related Antibodies
In Vivo

Anti-Mouse IL-25 Antibody (2C3) (500 μg/mouse, i.p., before colitis-induction) shows potent anti-inflammation effect in Oxazolone (HY-126360)-induced colitis mice models[1].
Anti-Mouse IL-25 Antibody (2C3) (500 μg/mouse, i.p., at 1 day before each OVA sensitization and 4 h before each OVA aerosolization) significantly reduces inflammation and prevents airway hyperresponsiveness in Ovalbumin (OVA)-induced allergic asthma mice models[2].
Anti-Mouse IL-25 Antibody (2C3) (500 μg, i.p., 4 or 12 h before each MCT) strongly inhibits allergy development in MCT (medium chain triglycerides)-induced allergy mice models[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Oxazolone (HY-126360)-induced colitis mice models (BALB/c, female)[1]
Dosage: 500 μg/mouse
Administration: Intraperitoneally injection, before colitis-induction
Result: Significantly reduced weight loss, diarrhea and gross bleeding.
Completely reversed shortening of the colon.
Had less damage to the intestinal walls, less ulceration, and reduced bloody stools.
Resulted in a significant decrease in the circulating numbers of eosinophils and levels of IL-4, IL-13.
Animal Model: Ovalbumin (OVA)-induced mice models of allergic asthma (BALB/c, 6-12 weeks)[2]
Dosage: 500 μg/dose
Administration: Intraperitoneally injection, at 1 day before each OVA sensitization and 4 h before each OVA aerosolization
Result: Resulted in a marked abrogation in airway hyperresponsiveness.
Significantly reduced the levels of cellular infiltration around the lung vasculature, goblet cell hyperplasia in the airways, and levels of antigen-specific serum IgE and eosinophil infiltration.
Decreased the levels of IL-5 and IL-13.
Animal Model: MCT (medium chain triglycerides)-induced allergy mice models (BALB/c, female, 7-8 weeks)[3]
Dosage: 500 μg
Administration: Intraperitoneally injection, 4 or 12 h before each MCT
Result: Suppressed development of shock (hypothermia) .
Decreased MMCP1.
Gene ID

140806  [NCBI]

Accession
Application

ELISA, FACS, Functional assay, Research in vivo
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molecular Weight

150 kDa

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Anti-Mouse IL-25 Antibody (2C3)]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Anti-Mouse IL-25 Antibody (2C3) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse IL-25 Antibody (2C3)Interleukin RelatedILIL-25ColitisAsthmaIL-13OvalbuminInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Anti-Mouse IL-25 Antibody (2C3)
Cat. No.:
HY-P990216
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (251 KB) Français - FR (251 KB) Deutsch - DE (251 KB) Norwegian - NO (251 KB) Español - ES (251 KB) Swedish - SV (251 KB) Italian - IT (251 KB) Portuguese - PT (251 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.