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  4. Anti-Mouse/Human Integrin β7 Antibody (FIB504)

Anti-Mouse/Human Integrin β7 Antibody (FIB504) 

Cat. No.: HY-P990207
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Anti-Mouse/Human Integrin β7 Antibody (FIB504) is an anti-mouse/human Integrin β7 IgG2a monoclonal antibody. Anti-Mouse/Human Integrin β7 Antibody (FIB504) can reduce the residence of type 2 innate lymphoid cells (ILC2s). Anti-Mouse/Human Integrin β7 Antibody (FIB504) can be used for researches on inflammation conditions and cancer such as lupus nephritis and glioma.

For research use only. We do not sell to patients.

Anti-Mouse/Human Integrin β7 Antibody (FIB504)

Anti-Mouse/Human Integrin β7 Antibody (FIB504) Chemical Structure

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Anti-Mouse/Human Integrin β7 Antibody (FIB504) Related Antibodies

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Description

Anti-Mouse/Human Integrin β7 Antibody (FIB504) is an anti-mouse/human Integrin β7 IgG2a monoclonal antibody. Anti-Mouse/Human Integrin β7 Antibody (FIB504) can reduce the residence of type 2 innate lymphoid cells (ILC2s). Anti-Mouse/Human Integrin β7 Antibody (FIB504) can be used for researches on inflammation conditions and cancer such as lupus nephritis and glioma[1][2].

Isotype

Rat IgG2a kappa
Recommend Isotype Controls
Species Reactivity

Human/Mouse
In Vivo

Anti-Mouse/Human Integrin β7 Antibody (FIB504) (500 μg, i.p., on day 7, 9 and 11) reduces the number of type 2 innate lymphoid cells (ILC2s) in female MRL-lpr mice with a spontaneous lupus model[1].
Anti-Mouse/Human Integrin β7 Antibody (FIB504) (100 μg/mL antibody pretreated MDSCs, i.v., single dose, on day 4 or day 7) does not significantly affect the survival period of C57BL/6 mice bearing GL261 or SB28 tumors[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Imiquimod (HY-B0180) (2.5 mg) induced female MRL-lpr mice (5-8 weeks and 16 weeks)[1]
Dosage: 500 μg
Administration: Intraperitoneal injection (i.p.), on day 7, 9 and 11
Result: Significantly reduced the residence of renal ILC2s.
Animal Model: 25000 GL261 or 10000 SB28 cells injected C57BL/6 mice (4 weeks)[2]
Dosage: 100 μg/mL antibody pretreated MDSCs
Administration: Intravenous injection (i.v.), single dose, on day 4 or day 7
Result: Did not significantly alter the survival period of mice.
Increased the number of macrophages.
Application

ELISA, FACS, Functional assay, Research in vivo
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molecular Weight

150 kDa

SMILES

[Anti-Mouse/Human Integrin β7 Antibody (FIB504)]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Anti-Mouse/Human Integrin β7 Antibody (FIB504) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse/Human Integrin β7 Antibody (FIB504)IntegrinIntegrin β7ILC2slupus nephritisGL261SB28Inhibitorinhibitorinhibit

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