Anti-IL-4 Antibody (MP4-25D2) 

Anti-IL-4 Antibody (MP4-25D2) is a kind of rat IgG1 κ chimeric antibody inhibitor, targeting to human IL-4. Anti-IL-4 Antibody (MP4-25D2) can neutralize human IL-4 (interleukin-4). Anti-IL-4 Antibody (MP4-25D2) can be used for the inflammation and immunology^[1][2].

Rat IgG1 kappa

Rat IgG1 kappa, Isotype Control

Human

IL-4

Anti-IL-4 Antibody (MP4-25D2) (10 μg/mL) induces human CD4⁺ T cells to differentiate into Th1 cells^[1].
Anti-IL-4 Antibody (MP4-25D2) (10 μg/mL, 48 h) reduces IL-9 levels in human CD4⁺ T cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

16189  [NCBI]

P07750

ELISA, FACS, Functional assay, Research in vivo

Unconjugated

The product can be reconstituted/diluted with sterile PBS or saline.

150 kDa

Liquid

Colorless to light yellow

[Anti-IL-4 Antibody (MP4-25D2)]

Please store the product under the recommended conditions in the Certificate of Analysis.

• 
  Immobilized IL-4 Protein, Human, HY-P70445 can bind Anti-IL-4 Antibody (MP4-25D2). The EC₅₀ for this effect is 24.47 ng/mL.

• [1]. Li L, Liu X, et al. TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy. Cell Metab. 2019 Jan 8;29(1):103-123.e5.  [Content Brief]

  [2]. Nakatsukasa H, et al. The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells. Nat Immunol. 2015 Oct;16(10):1077-84.  [Content Brief]