Anti-Canine PD-L1/B7-H1 Antibody (JC071)

Cat. No.: HY-P990114 Purity: ≥95.0%: Data Sheet
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Anti-Canine PD-L1/B7-H1 Antibody (JC071) is an anti-canine PD-L1/B7-H1 IgG1 monoclonal antibody. Anti-Canine PD-L1/B7-H1 Antibody (JC071) can specifically bind to CHO-PDL1 cells and K562-cCD20-cPD-L1 cells. Anti-Canine PD-L1/B7-H1 Antibody (JC071) can enhance the level of IFN-γ. Anti-Canine PD-L1/B7-H1 Antibody (JC071) is often used in western blot experiments.

For research use only. We do not sell to patients.

Anti-Canine PD-L1/B7-H1 Antibody (JC071) Chemical Structure

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Anti-Canine PD-L1/B7-H1 Antibody (JC071) Featured Recommendations:

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Description

Isotype

Mouse IgG1 kappa

Recommend Isotype Controls

Mouse IgG1 kappa, Isotype Control

Species Reactivity

Canine

IC₅₀ & Target

PD-L1/B7-H1

In Vitro

Anti-Canine PD-L1/B7-H1 Antibody (JC071) (0.2 μM, 96 h) significantly enhance IFN-γ production in canine peripheral blood mononuclear cells (PBMCs)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ELISA Assay^[1]

Cell Line:	PBMCs
Concentration:	0.2 μM
Incubation Time:	96 h
Result:	Increased the level of IFN-γ by about 6 times.

Gene ID

60533 [NCBI]

Accession

Q9EP73

Molecular Weight

150 kDa

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Anti-Canine PD-L1/B7-H1 Antibody (JC071)]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Purity: ≥95.0%

Select Batch:

Data Sheet (258 KB) SDS (251 KB)

COA (232 KB)

Inhibitory Antibodies User Guide (602 KB)

References

[1]. Choi JW, et al. Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function. PLoS One. 2020 Jul 2;15(7):e0235518. [Content Brief]

[2]. Yoshimoto S, et al. Validation of a PD-1/CD28 chimeric switch receptor to augment CAR-T function in dogs with spontaneous B cell lymphoma. iScience. 2024 Aug 31;27(9):110863. [Content Brief]

Anti-Canine PD-L1/B7-H1 Antibody (JC071) Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Canine PD-L1/B7-H1 Antibody (JC071)PD-1/PD-L1PD-1/Programmed death-ligand 1PD-L1/B7-H1IFN-γwestern blotInhibitorinhibitorinhibit

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