2. Signaling Pathways
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  4. Reference Standards

Reference Standards

Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.

Reference Standards Related Products (630):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-100561R
    Tempol (Standard)
    Tempol (Standard) is the analytical standard of Tempol. This product is intended for research and analytical applications. Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS).
    Tempol (Standard)
  • HY-100583R
    (-)-(S)-Equol (Standard)
    (-)-(S)-Equol (Standard) is the analytical standard of (-)-(S)-Equol. This product is intended for research and analytical applications. (-)-(S)-Equol is a high affinity ligand for estrogen receptor β with a Ki of 0.73 nM.
    (-)-(S)-Equol (Standard)
  • HY-100777R
    DACA (Standard)
    DACA (Standard) is the analytical standard of DACA. This product is intended for research and analytical applications. DACA inhibits two essential nuclear enzymes in vitro, DNA topoisomerase I and DNA topoisomerase (topo) II. DACA stabilises topo I, topo II alpha, and topo II beta cleavable complexes in human leukaemia CCRF-CEM cells.
    DACA (Standard)
  • HY-10009R
    Semagacestat (Standard)
    Semagacestat (Standard) is the analytical standard of Semagacestat. This product is intended for research and analytical applications. Semagacestat is a γ-secretase inhibitor, inhibits β-amyloid (Aβ42), Aβ38 and Aβ40 with IC50s of 10.9, 12 and 12.1 nM, respectively; also inhibits Notch signaling with IC50 of 14.1 nM. Semagacestat can be used for the research of alzheimer's?disease.
    Semagacestat (Standard)
  • HY-101184R
    T807 (Standard)
    T807 (Standard) is the analytical standard of T807. This product is intended for research and analytical applications. T807 a novel tau positron emission tomography (PET) tracer.
    T807 (Standard)
  • HY-W015451R
    2,7-Dihydroxynaphthalene (Standard)
    2,7-Dihydroxynaphthalene (Standard) is the analytical standard of 2,7-Dihydroxynaphthalene. This product is intended for research and analytical applications. 2,7-Dihydroxynaphthalene (2,7-DHN; Naphthalene-2,7-diol) is an aromatic substrate by the bacterial ABBA prenyltransferases NphB and SCO7190.
    2,7-Dihydroxynaphthalene (Standard)
  • HY-10172R
    IMD-0354 (Standard)
    IMD-0354 (Standard) is the analytical standard of IMD-0354. This product is intended for research and analytical applications. IMD-0354 (IKK2 Inhibitor V) is a selective IKKβ inhibitor which inhibits NF-κB activity. IMD0354 inhibits TNF-α induced NF-κB transcription activity with an IC50 of 1.2 uM.
    IMD-0354 (Standard)
  • HY-B1159R
    Nitroxoline (Standard)
    Nitroxoline (Standard) is the analytical standard of Nitroxoline. This product is intended for research and analytical applications. Nitroxoline (8-Hydroxy-5-nitroquinoline), an antibiotic, is an orally active antibiofilm agent. Nitroxoline reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc. Nitroxoline can be used for the urinary tract infections and cancer research.
    Nitroxoline (Standard)
  • HY-100875R
    Bisantrene (Standard)
    Bisantrene (Standard) is the analytical standard of Bisantrene. This product is intended for research and analytical applications. Bisantrene is a highly effective antitumor agent, it exerts its cytotoxicity by affecting DNA intercalation. Bisantrene targets eukaryotic type II topoisomerases. Bisantrene is a substrate of MDR1.
    Bisantrene (Standard)
  • HY-100144R
    Pirozadil (Standard)
    Pirozadil (Standard) is the analytical standard of Pirozadil. This product is intended for research and analytical applications. Pirozadil is a hypolipidemic agent.
    Pirozadil (Standard)
  • HY-109656R
    Diethylamino hydroxybenzoyl hexyl benzoate (Standard)
    Diethylamino hydroxybenzoyl hexyl benzoate (Standard) is the analytical standard of Diethylamino hydroxybenzoyl hexyl benzoate. This product is intended for research and analytical applications. Diethylamino hydroxybenzoyl hexyl benzoate is a photostable UV-A absorber.
    Diethylamino hydroxybenzoyl hexyl benzoate (Standard)
  • HY-10019R
    Varenicline (Standard)
    Varenicline (Standard) is the analytical standard of Varenicline. This product is intended for research and analytical applications. Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation.
    Varenicline (Standard)
  • HY-100991R
    FG 7142 (Standard)
    FG 7142 (Standard) is the analytical standard of FG 7142. This product is intended for research and analytical applications. FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 (ZK 39106; LSU-65) can increase tyrosine hydroxylation and cause upregulation of?β-adrenoceptors in mouse cerebral cortex.
    FG 7142 (Standard)
  • HY-W089845R
    Heneicosane (Standard)
    Heneicosane (Standard) is the analytical standard of Heneicosane (HY-W089845). This product is intended for research and analytical applications. Heneicosane is a royal-specific pheromone of insects (such as subterranean termites) and is an identification signal for queens and kings in termites. Heneicosane mediates royal recognition and the maintenance of social division of labor by being sensed by worker ants and triggering vibrations and antennal behaviors. Heneicosane can exert anti-inflammatory, analgesic and antipyretic activities by inhibiting the release of inflammatory mediators (such as prostaglandins and cytokines). At the same time, Heneicosane can also inhibit the mycelial growth of aflatoxin-producing fungi and inhibit the production of aflatoxin. Heneicosane can be used in insect chemical ecology research to analyze the regulatory mechanism of termite social behavior, and is also a potential target for new anti-inflammatory drugs.
    Heneicosane (Standard)
  • HY-13643R
    Daminozide (Standard)
    Daminozide (Standard) is the analytical standard of Daminozide. This product is intended for research and analytical applications. Daminozide, a plant growth regulator, is a selective inhibitor of the human KDM2/7 histone demethylases, with IC50s of 0.55, 1.5 and 2.1 μM for PHF8, KDM2A, and KIAA1718, respectively. Daminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested.
    Daminozide (Standard)
  • HY-101604R
    Atrimustine (Standard)
    Atrimustine (Standard) is the analytical standard of Atrimustine. This product is intended for research and analytical applications. Atrimustine is a conjugate of chlorambucil and β-estradiol benzoate with the antitumor activity.
    Atrimustine (Standard)
  • HY-100386R
    Ticlopidine (Standard)
    Ticlopidine (Standard) is the analytical standard of Ticlopidine. This product is intended for research and analytical applications. Ticlopidine (PCR 5332), an antithrombotic proagent, acts as an allosteric, noncompetitive inhibitor of CD39 with the IC50 of 81.7 μM. Ticlopidine blocks several NTPDase isoenzymes with IC50s of 170 μM and 149 μM for NTPDase2 and NTPDase3, respectively. Ticlopidine is an inhibitor of CYP2C19 human liver cytochrome. Ticlopidine inhibits CYP2C9 and CYP3A4 with IC50s of 26.0 and 32.3 μM, respectively.
    Ticlopidine (Standard)
  • HY-10182BR
    Laduviglusib trihydrochloride (Standard)
    Laduviglusib (trihydrochloride) (Standard) is the analytical standard of Laduviglusib (trihydrochloride). This product is intended for research and analytical applications. Laduviglusib (CHIR-99021) trihydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib trihydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib trihydrochloride is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib trihydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib trihydrochloride induces autophagy.
    Laduviglusib trihydrochloride (Standard)
  • HY-100609R
    4-P-PDOT (Standard)
    4-P-PDOT (Standard) is the analytical standard of 4-P-PDOT. This product is intended for research and analytical applications. 4-P-PDOT is a potent, selective and affinity Melatonin receptor (MT2) antagonist. 4-P-PDOT is >300-fold more selective for MT2 than MT1. 4-P-PDOT significantly counteracts Melatonin-mediated antioxidant effects (GSH/GSSG ratio, phospho-ERK, Nrf2 nuclear translocation, Nrf2 DNA-binding activity).
    4-P-PDOT (Standard)
  • HY-101404R
    DL-Homocysteine thiolactone hydrochloride (Standard)
    DL-Homocysteine thiolactone (hydrochloride) (Standard) is the analytical standard of DL-Homocysteine thiolactone (hydrochloride). This product is intended for research and analytical applications. DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.
    DL-Homocysteine thiolactone hydrochloride (Standard)