2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.

Liposome Related Products (839):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-154974
    LNP Lipid-8
    LNP Lipid-8 (11-A-M) is an ionizable single-tail multi-head lipid that can be used as a lipid nanoparticle (LNP) to deliver siRNA to T cells without targeting ligands. LNP Lipid-8 is more selective for T cells than other cell types such as hepatocytes. LNP Lipid-8 selectively delivers siRNA/sgRNA to T cells (especially CD8+ T cells) through endogenous lipid transport pathways, and can enter cells and release RNA through endocytosis to achieve gene silencing. LNP Lipid-8 loaded with GFP siRNA (siGFP) significantly led to GFP gene silencing in mouse models. LNP Lipid-8 showed good efficacy and safety in both cells and animals, without obvious liver targeting and toxicity. LNP Lipid-8 can be used for RNA delivery research in the fields of tumor immunotherapy and T cell-mediated autoimmune diseases.
    LNP Lipid-8
  • HY-W440999
    DSPE-N3
    DSPE-N3 is a lipid. DSPE-N3 can be used for the research of various biochemical. DSPE-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    DSPE-N3
  • HY-171306
    MK16
    		99.86%
    MK16 is a lipid material that can be used to construct blood-brain barrier penetrable lipid nanoparticles for mRNA delivery.
    MK16
  • HY-157950
    DSPE-PEG2000-triGalNAc ammonium
    		99.8%
    DSPE-PEG2K-triGalNAc is a polar lipid composed of DSPE and tri-N-acetylgalactosamine that can be used to construct liposomes target to asialoglycoprotein receptor (ASGPR).
    DSPE-PEG2000-triGalNAc ammonium
  • HY-P5366
    PEP1
    		Modulator 99.16%
    PEP1 is a biological active peptide. (PEP1 binds to POPC SLBs at Low Concentration, High Concentration of PEP1 Leads to POPC SLBs Lysis)
    PEP1
  • HY-142998
    Vaxfectin
    		99.94%
    Vaxfectin is a second-generation cationic lipid-based suspension that adjuvants effectively both pDNA and protein-based vaccines. Vaxfectin can boost the immune response against a range of pDNA-expressed pathogenic antigens in vivo. Vaxfectin can increase IgG titers and give rise to an IL-6 dependent enhancement of the humoral immune response without altering the Th1 type immune response. Vaxfectin can be studied for vaccine formulation.
    Vaxfectin
  • HY-W127499
    1,2-Dierucoyl-sn-glycero-3-phosphocholine
    		99.82%
    1,2-Dierucoyl-sn-glycero-3-phosphocholine (DEPC) is the composition of liposome membrane. 1,2-Dierucoyl-sn-glycero-3-phosphocholine is used for the preparation of liposomes and studying the properties of lipid bilayers. The GO (glucose oxidase) in the 1,2-Dierucoyl-sn-glycero-3-phosphocholine liposome shows the high activity.
    1,2-Dierucoyl-sn-glycero-3-phosphocholine
  • HY-W127351
    Cholesterol decanoate
    		98.0%
    Cholesterol decanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and capric acid. Cholesterol decanoate has several applications in the pharmaceutical industry, particularly as a bioactive compound with potential research potential for improving a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    Cholesterol decanoate
  • HY-149037A
    GL67 pentahydrochloride
    		98.60%
    GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection.
    GL67 pentahydrochloride
  • HY-157721
    1,2-Dibehenoyl-sn-glycero-3-phosphocholine
    1,2-Dibehenoyl-sn-glycero-3-phosphocholine (DBPC) is a phospholipid found in cell membranes. 1, 2-dibehenoyl-SN-glycero-3-phosphocholine can be used to generate micelles, liposomes, and other types of artificial membranes.
    1,2-Dibehenoyl-sn-glycero-3-phosphocholine
  • HY-144010
    18:1 PEG2000 PE ammonium
    		99.79%
    18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) can be used for drug delivery.
    18:1 PEG2000 PE ammonium
  • HY-W800805
    DOPE-Mal
    		98.68%
    DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.
    DOPE-Mal
  • HY-153186
    LNP Lipid-3
    		99.91%
    LNP Lipid-3 is an ionizable lipid that can be used to synthesize lipid nanoparticles. LNP Lipid-3 can be applied in the research of drug delivery.
    LNP Lipid-3
  • HY-145225
    DLin-K-C3-DMA
    		Chemical 98.59%
    DLin-K-C3-DMA, a cationic lipid, can be used in the synthesis of nucleic acid-lipid particle to delivery of nucleic acid.
    DLin-K-C3-DMA
  • HY-W127558
    Cholesterol-PEG 600
    Cholesterol-PEG 600 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Cholesterol-PEG 600
  • HY-W440821
    m-PEG-DMG (MW 2000)
    		≥98.0%
    m-PEG-DMG (MW 2000) is a PEG lipid for the preparation of liposomes and can be used in drug delivery studies.
    m-PEG-DMG (MW 2000)
  • HY-172723
    DSPE-PEG2000-T7
    DSPE-PEG2000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG2000-T7 can be used for drug delivery.
    DSPE-PEG2000-T7
  • HY-150241
    DOPE-NHS
    DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery.
    DOPE-NHS
  • HY-W440823A
    DSPE-PEG-Amine, MW 1000 ammonium
    		99.48%
    DSPE-PEG-Amine, MW 1000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 1000 (ammonium) can be converted to an aromatic aldehyde, which reacts with an acetone-protected aromatic hydrazine on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
    DSPE-PEG-Amine, MW 1000 ammonium
  • HY-160552
    244cis
    244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels.
    244cis