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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9804):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N7092S2
    D-Fructose-13C-1
    ≥98.0%
    D-Fructose-13C-1 is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
    D-Fructose-<sup>13</sup>C-1
  • HY-10163S
    Dabigatran-d4
    Dabigatran-d4 is deuterium labeled Dabigatran. Dabigatran (BIBR 953), an oral anticoagulant, is a reversible, potent, competitive direct thrombin inhibitor (Ki=4.5 nM). Dabigatran (BIBR 953) also inhibits thrombin-induced platelet aggregation (IC50=10 nM).
    Dabigatran-d<sub>4</sub>
  • HY-B1145S
    Chlorhexidine-d8 dihydrochloride
    Chlorhexidine-d8 (dihydrochloride) is the deuterium labeled Chlorhexidine dihydrochloride (HY-B1145). Chlorhexidine dihydrochloride is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine dihydrochloride binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine dihydrochloride has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine dihydrochloride can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis).
    Chlorhexidine-d<sub>8</sub> dihydrochloride
  • HY-W010256S
    D-Xylulose-1-13C
    99.22%
    D-Xylulose-1-13C is the 13C labeled D-Xylulose. D-xylulose is a precursor of the pentiol D-arabi.
    D-Xylulose-1-<sup>13</sup>C
  • HY-W002300S
    Boc-L-Valine-d8
    99.62%
    Boc-L-Valine-d8 is the deuterium labeled Boc-L-Valine.
    Boc-L-Valine-d<sub>8</sub>
  • HY-B0960S
    Sulfabenzamide-d4
    Sulfabenzamide-d4 is the deuterium labeled Sulfabenzamide (HY-B0960). Sulfabenzamide (N-Sulfanilylbenzamide) is an antimicrobial agent and usually consumed in combination with Sulfathiazole and Sulfacetamide. Sulfabenzamide is effective against Gram-positive and negative bacterial strains.
    Sulfabenzamide-d<sub>4</sub>
  • HY-N0390S10
    L-Glutamine-1,2-13C2
    ≥98.0%
    L-Glutamine-1,2-13C2 is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.
    L-Glutamine-1,2-<sup>13</sup>C<sub>2</sub>
  • HY-W015301S2
    Dimethyl adipate-d8
    ≥98.0%
    Dimethyl adipate-d8 is the deuterium labeled Dimethyl adipate.
    Dimethyl adipate-d<sub>8</sub>
  • HY-Y0366S2
    Lauric acid-d2
    99.80%
    Lauric acid-d2 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.
    Lauric acid-d<sub>2</sub>
  • HY-B0579S3
    Cyclosporin A-13C2,d4
    Cyclosporin A-13C2,d4 (Cyclosporine A-13C2,d4; Ciclosporin A-13C2,d4) is a 13C labeled Cyclosporin A (HY-B0579). Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 adhesion.
    Cyclosporin A-<sup>13</sup>C<sub>2</sub>,d<sub>4</sub>
  • HY-B0925S
    Oxacillin-13C6 sodium
    Oxacillin-13C6 (sodium) is the 13C6 labeled Oxacillin (sodium). Oxacillin sodium salt is a narrow-spectrum β-lactam antibiotic of the penicillin class.
    Oxacillin-<sup>13</sup>C<sub>6</sub> sodium
  • HY-N0108S
    Physcion-d3
    99.82%
    Physcion-d3 (Parietin-d3) is the deuterium labeled Physcion (HY-N0108). Physcion acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively. Physcion exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects.
    Physcion-d<sub>3</sub>
  • HY-Y1359S
    2-Methylimidazole-d6
    2-Methylimidazole-d6 is the deuterium labeled 2-Methylimidazole.
    2-Methylimidazole-d<sub>6</sub>
  • HY-145008S
    (±)9(10)-DiHOME-d4
    99.00%
    (±)9(10)-DiHOME-d4 is the deuterium labeled (±)9(10)-DiHOME.
    (±)9(10)-DiHOME-d<sub>4</sub>
  • HY-12715S1
    Yohimbine-d3
    ≥99.0%
    Yohimbine-d3 is the deuterium labeled Yohimbine (HY-12715).
    Yohimbine-d3
  • HY-113328S1
    Aminoadipic acid-d6
    Aminoadipic acid-d6 is deuterated labeled Aminoadipic acid (HY-113328). Aminoadipic acid is an intermediate in the metabolism of lysine and glycopurine.
    Aminoadipic acid-d<sub>6</sub>
  • HY-N1428S3
    Citric acid-13C3
    Citric acid-13C3 is the 13C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries.
    Citric acid-<sup>13</sup>C<sub>3</sub>
  • HY-W011297S1
    Methyl arachidonate-d8
    Methyl arachidonate-d8 is the deuterium labeled Arachidonic acid methyl ester.
    Methyl arachidonate-d<sub>8</sub>
  • HY-146712S
    N-(4-Hydroxyphenyl)acetamide sulfate-d3 sodium
    N-(4-Hydroxyphenyl)acetamide sulfate-d3 (sodium) is the deuterium labeled N-(4-Hydroxyphenyl)acetamide sulfate.
    N-(4-Hydroxyphenyl)acetamide sulfate-d<sub>3</sub> sodium
  • HY-10888S
    Istradefylline-13C,d3
    Istradefylline-13C,d3 is the 13C- and deuterium labeled Istradefylline. Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.
    Istradefylline-<sup>13</sup>C,d<sub>3</sub>