2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9980):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W141038S
    2-Ethyl-5-methylpyrazine-d5
    2-Ethyl-5-methylpyrazine-d5 is deuterated labeled 2-Ethyl-5-methylpyrazine.
    2-Ethyl-5-methylpyrazine-d<sub>5</sub>
  • HY-132504S
    Tianeptine Metabolite MC5-d4 sodium
    Tianeptine Metabolite MC5-d4 (sodium) is the deuterium labeled Tianeptine Metabolite MC5 sodium salt.
    Tianeptine Metabolite MC5-d<sub>4</sub> sodium
  • HY-B0202AS
    Irbesartan-d7 hydrochloride
    Irbesartan-d7 hydrochloride is deuterated labeled Irbesartan hydrochloride (HY-B0202A). Irbesartan (SR-47436) hydrochloride is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan hydrochloride can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan hydrochloride can be used for the research of high blood pressure, heart failure, and diabetic kidney disease.
    Irbesartan-d<sub>7</sub> hydrochloride
  • HY-W748200
    3-Hydroxypropionic acid-13C3 sodium
    3-Hydroxypropionic acid-13C3 sodium is the 13C labeled 3-Hydroxypropionic acid sodium (HY-W095705A). 3-Hydroxypropionic acid sodium, an endogenous metabolite, is a building block in the chemical synthesis.
    3-Hydroxypropionic acid-<sup>13</sup>C<sub>3</sub> sodium
  • HY-W014375S3
    DL-Arginine-d7 hydrochloride
    DL-Arginine-d7 hydrochloride is deuterium labeled DL-Arginine hydrochloride (HY-W014375). DL-Arginine ((±)-Arginine) hydrochloride is the racemic compound of L-Arginine (HY-N0455) and D-Arginine (HY-W016781). Arginine is an essential amino acid that requires additional supplementation in traumatic or diseased conditions. Arginine is involved in T cell activation, proliferation, and differentiation, and affects the function of immune cells.
    DL-Arginine-d<sub>7</sub> hydrochloride
  • HY-17504BS2
    Rosuvastatin-13C,d3 sodium
    Rosuvastatin-13C,d3 sodium is 13C and deuterated labeled Rosuvastatin sodium (HY-17504B). Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
    Rosuvastatin-<sub>13</sub>C,d<sub>3</sub> sodium
  • HY-165674S
    11-Dehydro-2,3-dinor thromboxane B2-d9
    11-dehydro-2,3-dinor Thromboxane B2-d9 (11-dehydo-2,3-dio TXB2-d9) is deuterium labeled 11-dehydro-2,3-dinor Thromboxane B2.
    11-Dehydro-2,3-dinor thromboxane B2-d<sub>9</sub>
  • HY-W013049S
    Docosanoic acid-d4
    Docosanoic acid-d4 (Behenic acid-4) is deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans.
    Docosanoic acid-d<sub>4</sub>
  • HY-10617AS
    Rucaparib-d8
    Rucaparib-d8 (AG014699-d8 ) is deuterium labeled Rucaparib. Rucaparib (AG014699) is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib has the potential for castration-resistant prostate cancer (CRPC) research.
    Rucaparib-d<sub>8</sub>
  • HY-13777S
    Zoledronic acid-d5
    Zoledronic acid-d5 is deuterated labeled Zoledronic Acid (HY-13777). Zoledronic Acid (Zoledronate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic Acid inhibits the differentiation and apoptosis of osteoclasts. Zoledronic Acid also has anti-cancer effects.
    Zoledronic acid-d<sub>5</sub>
  • HY-131325S
    Simeton-d3
    Simeton-d3 (N2,N4-Diethyl-6-(methoxy-d3)-1,3,5-triazine-2,4-diamine) is deuterium labeled Simeton.
    Simeton-d<sub>3</sub>
  • HY-165703S
    Prothioconazole-S-methyl-d3
    Prothioconazole-S-methyl-d3 (Prothioconazole-M01-d3) is deuterium labeled Prothioconazole-S-methyl.
    Prothioconazole-S-methyl-d<sub>3</sub>
  • HY-W741626
    N-Desmethyl selegiline-d5
    N-Desmethyl selegiline-d5 is the deuterium labeled N-Desmethyl selegiline.
    N-Desmethyl selegiline-d<sub>5</sub>
  • HY-N0097S5
    Guanosine-d13
    		99.4%
    Guanosine-d13 (DL-Guanosine-d13) is a deuterium of Guanosine (HY-N0097). Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity.
    Guanosine-d<sub>13</sub>
  • HY-W699430
    Norverapamil-d6 hydrochloride
    Norverapamil-d6 ((±)-Norverapamil-d6) hydrochloride is deuterium labeled Norverapamil (hydrochloride). Norverapamil hydrochloride ((±)-Norverapamil hydrochloride), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.
    Norverapamil-d<sub>6</sub> hydrochloride
  • HY-B1794S
    Thiethylperazine-d3
    Thiethylperazine-d3 is the deuterium labeled Thiethylperazinee (HY-B1794). Thiethylperazine, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine is also a selective ABCC1activator that reduces amyloid-β (Aβ) load in mice. Thiethylperazine has anti-emetic, antipsychotic and antimicrobial effects.
    Thiethylperazine-d<sub>3</sub>
  • HY-76595S1
    4-Bromo diphenyl ether-13C12
    4-Bromo diphenyl ether-13C12 is 13C labeled 1-Bromo-4-phenoxybenzene.
    4-Bromo diphenyl ether-<sup>13</sup>C<sub>12</sub>
  • HY-10913S
    Danegaptide-d5
    Danegaptide-d5 (GAP-134-d5) is deuterium labeled Danegaptide. Danegaptide (GAP-134) is a potent, selective and orally active gap-junction modifier with an antiarrhythmic effect.
    Danegaptide-d<sub>5</sub>
  • HY-W022039S
    (Benzyloxy)benzene-d2
    (Benzyloxy)benzene-d2 (NSC 77971-d2) is the deuterium labeled Benzyloxybenzene (HY-W022039).
    (Benzyloxy)benzene-d<sub>2</sub>
  • HY-106827S1
    Trimegestone-13C,d3
    Trimegestone-13C,d3 is 13C and deuterated labeled Trimegestone (HY-106827). Trimegestone (RU 27987) is an orally active 19-norpregnane progestin. Trimegestone binds to progesterone receptor (PR) with an IC50 value of 3.3 nM (rat PR). Trimegestone increases alkaline phosphatase activity (EC50=0.1 nM) but not luciferase activity. Trimegestone also shows a weak antiandrogenic activity (weak androgen receptor affinity). Trimegestone can be used in studies of contraception or menopausal syndromes.
    Trimegestone-<sup>13</sup>C,d<sub>3</sub>