2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9980):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-101491S
    SR-18292-d9
    SR-18292-d9 is the deuterium labeled SR-18292 (HY-101491). SR-18292 is a PPAR gamma coactivator-1α (PGC-1α) inhibitor, which increases PGC-1α acetylation, suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes.
    SR-18292-d<sub>9</sub>
  • HY-Y0785S
    Glyoxal-d2
    Glyoxal-d2 is the deuterium labeled Glyoxal (HY-Y0785). Glyoxal is a cytotoxic α-oxoaldehyde. Glyoxal induces cell damage and promotes protein glycation to form advanced glycation end-products (AGEs). Glyoxal is promising for research of oxidative stress-related diseases (such as atherosclerosis, cataract, Alzheimer's disease), and the formation of calcium oxalate kidney stones.
    Glyoxal-d<sub>2</sub>
  • HY-131932S
    N-Desethyl-dorzolamide-d3 hydrochloride
    N-Desethyl-dorzolamide-d3 hydrochloride is deuterated labeled N-Desethyl-dorzolamide.
    N-Desethyl-dorzolamide-d<sub>3</sub> hydrochloride
  • HY-W641639S
    2-Cyano-3,3-diphenylacrylic acid-d10
    2-Cyano-3,3-diphenylacrylic acid-d10 is deuterium labeled 2-Cyano-3,3-diphenylacrylic acid.
    2-Cyano-3,3-diphenylacrylic acid-d<sub>10</sub>
  • HY-13632S2
    Exemestane-d3
    Exemestane-d3 is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research.
    Exemestane-d<sub>3</sub>
  • HY-W654130
    Daunorubicin-13C,d3
    Daunorubicin-13C,d3 is 13C and deuterium labeled Daunorubicin. Daunorubicin (Daunomycin) is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin inhibits DNA and RNA synthesis. Daunorubicin is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin is also an anthracycline antibiotic. Daunorubicin can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor.
    Daunorubicin-<sup>13</sup>C,d<sub>3</sub>
  • HY-W000854S
    3-Methoxybenzeneboronic acid-d3
    3-Methoxybenzeneboronic acid-d3 is the deuterium labeled 3-Methoxybenzeneboronic acid (HY-W000854). 3-Methoxybenzeneboronic acid (3-Methoxyphenylboronic acid) is a boronic acid derivative. 3-Methoxybenzeneboronic acid shows best suitable binding pattern at the active site by interacting non-covalently with amino acid residues of proteins. 3-Methoxybenzeneboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    3-Methoxybenzeneboronic acid-d<sub>3</sub>
  • HY-B0419S
    Manidipine-d4
    Manidipine-d4 is the deuterium labeled Manidipine (HY-B0419). Manidipine is an orally active calcium channel antagonist. Manidipine regulates the expression of cytokines (IL-1β, IL-6). Manidipine has a hypotensive effect. Manidipine can be used in the study of cardiovascular diseases (such as hypertension, myocardial ischemia-reperfusion injury, ventricular hypertrophy), kidney diseases (such as glomerular diseases), and epilepsy.
    Manidipine-d<sub>4</sub>
  • HY-125140S
    ω-3 Arachidonic Acid-d8
    ω-3 Arachidonic Acid-d8 is the deuterium labeled ω-3 Arachidonic Acid.
    ω-3 Arachidonic Acid-d<sub>8</sub>
  • HY-126042S4
    (±)-Lisofylline-d4
    (±)-Lisofylline-d4 ((±)-Lisophylline-d4) is deuterium labeled (±)-Lisofylline. (±)-Lisofylline ((±)-Lisophylline) is the racemate of Lisofylline. Lisofylline inhibits the generation of phosphatidic acid and free fatty acids. Lisofylline also blocks the release of pro-inflammatory cytokines in oxidative tissue injury, in response to cancer chemotherapy and in experimental sepsis. Lisofylline can be used for Type 1 diabetes research.
    (±)-Lisofylline-d<sub>4</sub>
  • HY-W742416
    3-Mercapto-3-methylbutyl-d6 Formate
    3-Mercapto-3-methylbutyl-d6 Formate is deuterated labeled 3-Mercapto-3-methylbutyl Formate.
    3-Mercapto-3-methylbutyl-d6 Formate
  • HY-RS29484
    Tnxb Mouse Pre-designed siRNA Set A
    Tnxb Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tnxb gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Components

    Tnxb siRNA-1: 5 nmol (HPLC)

    Tnxb siRNA-2: 5 nmol (HPLC)

    Tnxb siRNA-3: 5 nmol (HPLC)

    siRNA Negative Control: 5 nmol (HPLC)

    FAM-labeled siRNA Negative Control: 5 nmol (HPLC)

    GAPDH siRNA Positive Control: 5 nmol (HPLC)
    Tnxb Mouse Pre-designed siRNA Set A
  • HY-W014612S
    Eugenol acetate-d3
    Eugenol acetate-d3 is the deuterated labeled Eugenol acetate (HY-W014612). Eugenol acetate (Eugenyl acetate) is an antibacterial, anticancer, anti-inflammatory and antioxidant. Eugenol acetate inhibits NF-κB and enhances the expression of p53 and p21 (WAF1). Eugenol acetate can prevent chemically induced skin cancer, inhibit cancer cell proliferation and induce apoptosis.
    Eugenol acetate-d<sub>3</sub>
  • HY-W744647
    cis-4-Heptenal-D2
    cis-4-Heptenal-d2 is deuterated labeled cis-4-Heptenal.
    cis-4-Heptenal-D2
  • HY-143850S
    Methyl diethyldithiocarbamate-d3
    Methyl diethyldithiocarbamate-d3 is the deuterium labeled Methyl diethyldithiocarbamate.
    Methyl diethyldithiocarbamate-d<sub>3</sub>
  • HY-151995S
    1,1',1''-(1,2,3-Propanetriyl-1,1,2,3,3-d5) tri-(11Z)-11-heptadecenoate
    1,1',1''-(1,2,3-Propanetriyl-1,1,2,3,3-d5) tri-(11Z)-11-heptadecenoate is deuterium labeled 1,1',1''-(1,2,3-Propanetriyl-1,1,2,3,3) tri-(11Z)-11-heptadecenoate.
    1,1',1''-(1,2,3-Propanetriyl-1,1,2,3,3-d<sub>5</sub>) tri-(11Z)-11-heptadecenoate
  • HY-132475S
    rac-Duloxetine-d3 oxalate
    rac Duloxetine 3-Thiophene Isomer-d3 Oxalate is a stable isotope of Duloxetine.
    rac-Duloxetine-d<sub>3</sub> oxalate
  • HY-W654409
    1,1,1,3,3,3-Hexafluoropropan-2-ol-d2
    1,1,1,3,3,3-Hexafluoropropan-2-ol-d2 (Hexafluoroisopropyl alcohol-d2) is deuterium labeled 1,1,1,3,3,3-Hexafluoropropan-2-ol.
    1,1,1,3,3,3-Hexafluoropropan-2-ol-d<sub>2</sub>
  • HY-W017374S2
    4-Ethyl-2-methoxyphenol-d2
    4-Ethyl-2-methoxyphenol-d2 is deuterated labeled 4-Ethyl-2-methoxyphenol.
    4-Ethyl-2-methoxyphenol-d<sub>2</sub>
  • HY-B0847S
    Propiconazole-d7
    Propiconazole-d7 is the deuterium labeled Propiconazole. Propiconazole is a broad-spectrum triazole fungicide that inhibits the conversion of lanosterol to ergosterol, leading to fungal cell membrane disruption. Propiconazole inhibits S. cerevisiae, but not rat liver, microsomal cytochrome P450 (IC50s=0.04 and >200 μM, respectively). Propiconazole inhibits the growth of T. deformans and R. stolonifer (ED50s=0.073 and 4.6 μg/mL, respectively). Propiconazole increases production of reactive oxygen species (ROS).
    Propiconazole-d<sub>7</sub>