2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9980):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W032013S2
    1-Octanol-d2-1
    1-Octanol-d2-1 is deuterated labeled 1-Octanol (HY-W032013). 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents. 1-Octanol is a highly attractive biofuel with diesel-like properties.
    1-Octanol-d<sub>2</sub>-1
  • HY-W654139
    5'-Deoxy-5'-(methylthio)adenosine-d3
    5'-Deoxy-5'-(methylthio)adenosine-d3 is deuterium labeled 5'-Methylthioadenosine. 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis.
    5'-Deoxy-5'-(methylthio)adenosine-d<sub>3</sub>
  • HY-B1895S1
    Levodropropizine-d5
    Levodropropizine-d5 ((S)-(-)-Dropropizine-d5) is deuterium labeled Levodropropizine. Levodropropizine (DF-526) is an orally active histamine receptor inhibitor, Levodropropizine is an effective and very well tolerated peripheral antitussive agent.
    Levodropropizine-d<sub>5</sub>
  • HY-N1952S
    Isoeugenol-d3
    Isoeugenol-d3 is deuterated labeled Isoeugenol (HY-N1952). Isoeugenol is an essential oil constituent of nutmeg, clove, and cinnamon. Isoeugenol inhibits growth of Escherichia coli and Listeria innocua with MICs of 0.6 mg/mL and 1 mg/mL, respectively.
    Isoeugenol-d<sub>3</sub>
  • HY-W653769
    Deltamethrin-d5 (Mixture of Diastereomers)
    Deltamethrin-d5 (Mixture of Diastereomers) is the deuterium labeled Deltamethrin (Mixture of Diastereomers).
    Deltamethrin-d<sub>5</sub> (Mixture of Diastereomers)
  • HY-W082452S
    N-Boc-N-methoxy-N-methyl-L-phenyl-alaninamide-d5
    N-Boc-N-methoxy-N-methyl-L-phenyl-alaninamide-d5 is the deuterium labeled Picoxystrobin. Picoxystrobin is a primary strobilurin fungicide that is widely applied for plant disease control. Picoxystrobin inhibits mitochondrial respiration via blocking elect
    N-Boc-N-methoxy-N-methyl-L-phenyl-alaninamide-d<sub>5</sub>
  • HY-W013113S
    Bis(2,2,6,6-tetramethylpiperidin-4-yl) decanedioate-d24
    Bis(2,2,6,6-tetramethylpiperidin-4-yl) decanedioate-d24 (Sebacic acid bis(2,2,6,6-tetramethyl-4-piperidyl) ester-d24) is deuterium labeled BTMPS.
    Bis(2,2,6,6-tetramethylpiperidin-4-yl) decanedioate-d<sub>24</sub>
  • HY-121944S
    Ricinine-d3
    Ricinine-d3 is the deuterium labeled Ricinine. Ricinine exhibits hepatoprotection in CCl4 -induced liver damage.
    Ricinine-d<sub>3</sub>
  • HY-114518S2
    Butenafine-d4
    Butenafine-d4 (KP363-d4) is the deuterium labeled Butenafine (HY-114518). Butenafine (KP363) is a potent and broad spectrum benzylamine antifungal agent. Butenafine inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation, leading to a deficiency of the fungal cell membranes. Butenafine is effective against dermatophytes infections, such as ?tinea pedis, ?tinea cruris, tinea versicolor.
    Butenafine-d<sub>4</sub>
  • HY-135334S
    ACP-5862-d4
    ACP-5862-d4 is deuterium labeled ACP-5862. ACP-5862 is a major active, circulating, pyrrolidine ring-opened metabolite of Acalabrutinib with an IC50 of 5.0 nM for Bruton tyrosine kinase (BTK). ACP‐5862 is a weak time‐dependent inactivator of CYP3A4 and CYP2C8. Acalabrutinib is an orally active, irreversible, and highly selective BTK inhibitor, with an IC50 of 3 nM and EC50 of 8 nM.
    ACP-5862-d<sub>4</sub>
  • HY-12199S1
    Pitolisant-d6
    Pitolisant-d6 (Tiprolisant-d6) is deuterium labeled Pitolisant. Pitolisant is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor (Ki=0.16 nM).
    Pitolisant-d<sub>6</sub>
  • HY-166363S
    Beraprost-d3
    Beraprost-d3 (TRK-100-d3) is deuterium labeled (Rac)-Beraprost. (Rac)-Beraprost ((Rac)-ML 1229) is an orally active prostacyclin analog that inhibits the release of Ca2+ from intracellular storage sites by binding to prostacyclin membrane receptors (Prostaglandin Receptor), leading to relaxation of smooth muscle cells and vasodilation. Beraprost has vasodilatory, antiplatelet, and cytoprotective effects, making it promising for research in the field of cardiovascular diseases, such as thromboangiitis obliterans and atherosclerosis.
    Beraprost-d<sub>3</sub>
  • HY-B0558S
    Carbimazole-d5
    Carbimazole-d5 is deuterium labeled Carbimazole. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research.
    Carbimazole-d<sub>5</sub>
  • HY-113202S
    Stearoyl-L-carnitine-d3
    Stearoyl-L-carnitine-d3 is the deuterium labeled Stearoylcarnitine. Stearoylcarnitine, a fatty ester lipid molecule, is an endogenous metabolite. Stearoylcarnitine can be used as PKC inhibitor. Stearoylcarnitine accumulates in β cells, leading to arrest of insulin synthesis and energy deficiency in type 2 diabetes mouse. Stearoylcarnitine inhibits lecithin cholesterol acyltransferase (LCAT) in rat and rabbits plasma. Stearoylcarnitine acts as a metabolomics biomarker for Parkinson’s disease. Stearoylcarnitine is a less potent inhibitor of GlyT2.
    Stearoyl-L-carnitine-d<sub>3</sub>
  • HY-N9933S
    Tauro-β-muricholic acid-d4-1 sodium
    Tauro-β-muricholic acid-d4-1 (T-βMCA-d4-1) sodium is the deuterium labeled Tauro-β-muricholic acid (HY-N9933).
    Tauro-β-muricholic acid-d<sub>4</sub>-1 sodium
  • HY-124245S
    3-Hydroxy desloratadine-d4
    3-Hydroxy desloratadine-d4 is the deuterium labeled 3-Hydroxy desloratadine[1].
    3-Hydroxy desloratadine-d<sub>4</sub>
  • HY-12857S2
    Brigatinib-d11
    Brigatinib-d11 (AP-26113-d11) is deuterium labeled Brigatinib. Brigatinib (AP-26113) is a highly potent, selective and orally active ALK inhibitor, with an IC50 of 0.6 nM. Brigatinib can be used for research of NSCLC.
    Brigatinib-d<sub>11</sub>
  • HY-W327895S
    Tris(4-chlorophenyl)methanol-13C19
    Tris(4-chlorophenyl)methanol-13C19 is 13C labeled Tris(4-chlorophenyl)methanol.
    Tris(4-chlorophenyl)methanol-<sup>13</sup>C<sub>19</sub>
  • HY-165682S
    Altenuisol-d3
    Altenuisol-d3 is deuterium labeled Altenuisol.
    Altenuisol-d<sub>3</sub>
  • HY-W741546S
    L-threo-Ritalinic Acid-d5 trifluoroacetate
    L-threo-Ritalinic Acid-d5 (TFA) is deuterium-labeled L-threo-Ritalinic Acid (HY-W741546).
    L-threo-Ritalinic Acid-d<sub>5</sub> trifluoroacetate