Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (9979):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W016562S1

Hippuric acid-d₂		99.83%
Hippuric acid-d₂ is the deuterium labeled Hippuric acid. Hippuric Acid (2-Benzamidoacetic acid), an acyl glycine produced by the conjugation of benzoic acid and glycine, is a normal component in urine as a metabolite of aromatic compounds from food.

HY-N0830BS1

Palmitic acid-¹³C₁₆ sodium		99.1%
Palmitic acid-¹³C₁₆ sodium is the ¹³C-labeled Palmitic acid sodium. Palmitic acid sodium is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid sodium can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells.

HY-B0228S13

Adenosine-¹³C₁₀		99.63%
Adenosine-¹³C₁₀ (Adenine riboside-¹³C₁₀; D-Adenosine-¹³C₁₀) is ¹³C-labeled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.

HY-W016823S

p-Tyramine-d₄ hydrochloride		≥99.90%
p-Tyramine-d₄ (hydrochloride) is the deuterium labeled Tyramine hydrochloride. Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods.

HY-N0667S2

L-Asparagine-¹⁵N₂ monohydrate		99.0%
L-Asparagine-¹⁵N₂ monohydrate is the ¹⁵N-labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.

HY-N0473S

L-Tyrosine-d₄		98.0%
L-Tyrosine-d₄ is a deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0067S1

γ-Aminobutyric acid-d₂		99.95%
γ-Aminobutyric acid-d₂ is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].

HY-N0390S6

L-Glutamine-¹³C₅,¹⁵N₂		98.0%
L-Glutamine-¹³C₅,¹⁵N₂ is the ¹³C- and ¹⁵N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.

HY-132949S

Decanoyl-L-carnitine-d₃ chloride		99.94%
Decanoyl-L-carnitine-d₃ (chloride) is the deuterium labeled Decanoyl-L-carnitine chloride.

HY-N0650S11

L-Serine-d₇		99.97%
L-Serine-d₇ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-B2176S5

ATP-¹⁵N₅ dilithium		99.0%
ATP-¹⁵N₅ (Adenosine 5'-triphosphate-¹⁵N₅) dilithium is ¹⁵N labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.

HY-W259489S

Picolinic acid-d₄		99.99%
Ppicolinic-3,4,5,6-d₄ acid is the deuterium labeled Ppicolinic acid.

HY-B0075S

Melatonin-d₄		99.70%
Melatonin-d₄ is deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Antioxidative and anti-inflammatory properties. Melatonin is a selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation.

HY-W015229S

3-Indolepropionic acid-d₂		99.47%
3-Indolepropionic acid-d₂ is the deuterium labeled 3-Indolepropionic acid. 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease.

HY-134928AS

Pyridinium bisretinoid A2E-d₄ TFA
Pyridinium bisretinoid A2E-d₄ TFA is the deuterium-labeled Pyridinium bisretinoid A2E (HY-134928). Pyridinium bisretinoid A2E (A2E)is an initiator of blue-light-induced apoptosis. Photoactivation of Pyridinium bisretinoid A2E mediates autophagy and the production of reactive oxygen species.

HY-W099602S

Dodecane-d₂₆		99.6%
Dodecane-d₂₆ is the deuterium labeled Dodecane.

HY-Y0069S

N-Acetylglycine-d₅		99.0%
N-Acetylglycine-d₅ (Aceturic acid-d₅) is the deuterium labeled N-Acetylglycine (HY-Y0069). N-Acetylglycine (Aceturic acid) is a minor constituent of numerous foods. N-Acetylglycine is a flavor enhancer which elicits Monosodium glutamate (MSG)-like sensory experiencesN-Acetylglycine.

HY-B0322S1

Sulfamethoxazole-¹³C₆		99.80%
Sulfamethoxazole-¹³C₆ (Ro 4-2130-¹³C₆) is a ¹³C labeled Sulfamethoxazole (HY-B0322). Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis.

HY-W015309S1

Decanoic acid-d₁₉		98.4%
Decanoic acid-d₁₉9 is the deuterium labeled Decanoic acid. Decanoic acid, a component of medium chain triclycerides, is a brain-penetrant and non-competitive inhibitor of AMPA receptor. Decanoic acid has antiseizure effects.

HY-14654S

Aspirin-d₃		98.51%
Aspirin-d₃ is the deuterium labeled Aspirin (HY-14654). Aspirin (Acetylsalicylic acid) is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC₅₀ values of 5 and 210 μg/mL, respectively. Aspirin induces apoptosis. Aspirin inhibits the activation of NF-κB. Aspirin also inhibits platelet prostaglandin synthetase, and can prevent coronary artery and cerebrovascular thrombosis.

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