Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (9979):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-156326S1

(3E,5Z)-Octadien-2-one-¹³C₂
(3E,5Z)-Octadien-2-one-¹³C₂ is ¹³C labeled (3E,5Z)-Octadien-2-one.

HY-W719560S

Flupyrsulfuron-methyl-d₆
Flupyrsulfuron-methyl-d₆ is deuterium labeled Methyl 2-(N-((4,6-dimethoxypyrimidin-2-yl)carbamoyl)sulfamoyl)-6-(trifluoromethyl)nicotinate.

HY-W014888S

Benzy(phenyl)sulfane-d₂
Benzy(phenyl)sulfane-d2 (Benzyl phenyl sylphide-d2) is the deuterium labeled Benzyl(phenyl)sulfane (HY-W014888).

HY-14877S1

Anagliptin-d₇
Anagliptin-d₇ (SK-0403-d₇) is deuterium labeled Anagliptin. Anagliptin (SK-0403) is a highly selective, potent, orally active inhibitor of dipeptidyl peptidase 4 (DPP-4), with an IC₅₀ of 3.8 nM, and less selective at DPP-8 and DDP-9 with IC₅₀s of 68 nM and 60 nM, respectively.

HY-131100S

Homo Sildenafil-d₅
Homo Sildenafil-d₅ is the deuterium labeled Homo Sildenafil. Homo Sildenafil, an analog of Sildenafil, acts as a phosphodiesterase inhibitor.

HY-W020691S

Lactide-d₆
Lactide-d₆ is a deuterium labeled Lactide.

HY-B0152S3

Adenine-¹³C₅
Adenine-¹³C₅ (6-Aminopurine-¹³C₅; Vitamin B4-¹³C₅) is ¹³C-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

HY-W010950S

Flecainide-d₃
Flecainide-d₃ is the deuterium labeled Flecainide. Flecainide is an orally active antiarrhythmic agent. Flecainide can block sodium channels and inhibit calcium ion release mediated by the cardiac ryanodine receptor (RyR2). Flecainide can be used in the research of diseases such as catecholaminergic polymorphic ventricular tachycardia (CPVT).

HY-165637S

(±)11(12)-DiHET-d₁₁
(±)11(12)-DiHET-d₁₁ is deuterium labeled (±)11(12)-DiHET.

HY-W377440

2-(Methyl-d₃)phenol
2-(Methyl-d₃)phenol is the deuterium labeled 2-(Methyl)phenol.

HY-N1914S

Ergothioneine-d₃
Ergothioneine-d₃ is the deuterium labeled Ergothioneine. Ergothioneine, an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant.

HY-161679S

Pyruvate Carboxylase-IN-3
Pyruvate Carboxylase-IN-3 (Compd 36) is a potent Pyruvate Carboxylase inhibitor. Pyruvate Carboxylase-IN-3 inhibits hepatocellular carcinoma cells activity with an IC₅₀ of 4.3 μM.

HY-B0150S3

Nicotinamide-d₃
Nicotinamide-d₃ (Niacinamide-d₃) is deuterium labeled Nicotinamide. Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC₅₀: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD₊, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity.

HY-170014S

2-Hydroxyethylflurazepam-d₄ (CRM)
2-Hydroxyethylflurazepam-d₄ (CRM) is deuterium labeled 2-Hydroxyethylflurazepam (CRM).

HY-N7436S

Methyl propyl disulfide-d₃
Methyl propyl disulfide-d₃ is deuterated labeled Methyl propyl disulfide (HY-N7436). Methyl propyl disulfide is an volatile sulfur-containing compound produced in garlic and onions with anticaner effect.

HY-13553S1

Anidulafungin-¹³C₆
Anidulafungin-¹³C₆ (LY303366-¹³C₆) is ¹³C labeled Anidulafungin. Anidulafungin is a new semisynthetic echinocandin with antifungal potency.

HY-17390BS

Loxapine-d₈ hydrochloride
Loxapine-d₈ hydrochloride is the deuterium labeled Loxapine. Loxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent.

HY-W743954

Nicergoline impurity 11-d₃
Nicergoline impurity 11-d₃ is deuterium labeled ((6aR,9R,10aS)-10a-Methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol (Nicergoline Impurity).

HY-W286743S

CML-d₄		99.76%
CML-d₄ is the deuterium labeled Fmoc-L-Lys (Boc)-OH.

HY-N5134S5

5'-Guanylic acid-¹³C₁₀,¹⁵N₅ dilithium
5'-Guanylic acid-¹³C₁₀,¹⁵N₅ (5'-GMP-¹³C₁₀,¹⁵N₅ dilithium; 5'-guanosine monophosphate-¹³C₁₀,¹⁵N₅) dilithium is ¹³C and ¹⁵N-labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.

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