2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9979):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-Y1805S
    1,2,3,4-Tetrahydronaphthalene-d4
    1,2,3,4-Tetrahydronaphthalene-d4 (Tetralin solvent-d4) is the deuterium labeled 1,2,3,4-Tetrahydronaphthalene (HY-Y1805).
    1,2,3,4-Tetrahydronaphthalene-d<sub>4</sub>
  • HY-B0607S
    Nitisinone-d3
    Nitisinone-d3 (NTBC-d3) is deuterium labeled Nitisinone. Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism.
    Nitisinone-d<sub>3</sub>
  • HY-17507S4
    Pantoprazole-d4
    Pantoprazole-d4 (BY1023-d4) is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI). Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142).
    Pantoprazole-d<sub>4</sub>
  • HY-W097565S
    Pyroxsulam Metabolite ADTP-d6
    Pyroxsulam Metabolite ADTP-d6 (5,7-Dimethoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-amine-d6) is deuterium labeled 5,7-Dimethoxy-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine.
    Pyroxsulam Metabolite ADTP-d<sub>6</sub>
  • HY-78726S2
    Fosamprenavir-13C6
    Fosamprenavir-13C6 is the 13C-labeled Fosamprenavir (HY-78726). Fosamprenavir is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir can be used for the study of human immunodeficiency virus (HIV-1) infection.
    Fosamprenavir-<sup>13</sup>C<sub>6</sub>
  • HY-B1451S
    Imidapril-d3 hydrochloride
    Imidapril-d3 hydrochloride (TA-6366-d3) is the deuterium labeled Imidapril hydrochloride. Imidapril hydrochloride (TA-6366) is the hydrochloride salt of Imidapril, an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
    Imidapril-d<sub>3</sub> hydrochloride
  • HY-W653893
    Taurocholic acid-d5 sodium
    Taurocholic acid-d5 (sodium) is deuterium labeled Taurocholic acid (sodium). Taurocholic acid sodium (Sodium taurocholate) has marked bioactive effects such as an inhibitory potential against hepatic artery ligation induced biliary damage by upregulation of VEGF-A expression. Taurocholic acid sodium has immunoregulation effect.
    Taurocholic acid-d<sub>5</sub> sodium
  • HY-50878S1
    Crizotinib-d8
    Crizotinib-d8 (PF-02341066-d8) is deuterium labeled Crizotinib. Crizotinib (PF-02341066) is an orally bioavailable, ATP-competitive ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively. Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. Crizotinib is also a ROS1 inhibitor. Crizotinib has effective tumor growth inhibition.
    Crizotinib-d<sub>8</sub>
  • HY-N1920S
    DL-Menthone-d8
    DL-Menthone-d8 is deuterated labeled DL-Menthone.
    DL-Menthone-d<sub>8</sub>
  • HY-156352S
    Ethyl (S)-2-hydroxy-3-methylbutyrate-d5
    Ethyl (S)-2-hydroxy-3-methylbutyrate-d5 is deuterated labeled Ethyl (S)-2-hydroxy-3-methylbutyrate.
    Ethyl (S)-2-hydroxy-3-methylbutyrate-d<sub>5</sub>
  • HY-16508S1
    Ulipristal acetate-d3
    Ulipristal acetate-d3 (CDB-2914-d3) is deuterium labeled Ulipristal acetate. Ulipristal acetate (CDB-2914) is an orally active, selective progesterone receptor modulator (SPRM). Ulipristal acetate stimulates the autophagic response selectively in leiomyoma cells. Ulipristal acetate has the potential for benign gynecological conditions treatment, such as uterine myoma.
    Ulipristal acetate-d<sub>3</sub>
  • HY-W814363
    Octadec-9-enoic acid-13C5
    Octadec-9-enoic acid-13C5 is a deuterated labeled Octadec-9-enoic acid-13C5.
    Octadec-9-enoic acid-<sup>13</sup>C<sub>5</sub>
  • HY-W654304
    Oxonic Acid -13C2,15N3 potassium salt hydrate
    Oxonic Acid -13C2,15N3 (potassium salt hydrate) is 13C and 15N labeled Oxonic Acid (potassium salt hydrate).
    Oxonic Acid -<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N<sub>3</sub> potassium salt hydrate
  • HY-B0259S
    (rac)-Indapamide-d3
    (rac)-Indapamide-d3 is a labelled racemic Indapamide. Indapamide is an orally active sulphonamide diuretic agent, that can reduce blood pressure by decreasing vascular reactivity and peripheral vascular resistance. Indapamide is also can reduce left ventricular hypertrophy.
    (rac)-Indapamide-d<sub>3</sub>
  • HY-143854S
    N-Nitroso-N-methyl-4-aminobutyric acid-d3
    N-Nitroso-N-methyl-4-aminobutyric acid-d3 is the deuterium labeled N-Nitroso-N-methyl-4-aminobutyric acid.
    N-Nitroso-N-methyl-4-aminobutyric acid-d<sub>3</sub>
  • HY-B1438S2
    Canrenone-d7
    		99.60%
    Canrenone-d7 (Aldadiene-d7 ) is deuterium labeled Canrenone. Canrenone (Aldadiene) is an aldosterone antagonist extensively used as a diuretic agent.
    Canrenone-d<sub>7</sub>
  • HY-B0763S
    Ibudilast-d3
    Ibudilast-d3 (KC-404-d3) is the deuterium labeled Ibudilast. Ibudilast (KC-404) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia.
    Ibudilast-d<sub>3</sub>
  • HY-113455S1
    9(S)-HODE-13C18
    9(S)-HODE-13C18 ((+)-α-Dimophecolic acid-13C18) is 13C labeled 9S-HODE. 9S-HODE (Alpha-dimorphecolic acid) is an octadecadienoic acid and the main active derivative of linoleic acid, which can reduce the viability of HL-60 cells and induce apoptosis. 9S-HODE is rich in lipid peroxidation (LPO) products and is almost an ideal marker for LPO.
    9(S)-HODE-<sup>13</sup>C<sub>18</sub>
  • HY-W751072
    Hexamethylenimine-d4
    Hexamethylenimine-d4 (1-Azacycloheptane-d4) is the deuterium labeled Hexamethylenimine.
    Hexamethylenimine-d<sub>4</sub>
  • HY-114697S
    DSG Crosslinker-d4
    DSG Crosslinker-d4 is the deuterium labeled DSG Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified.
    DSG Crosslinker-d<sub>4</sub>