2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9979):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-163992S
    VTMTRDTSISTAYMELSR-(Ile-13C6,15N)
    VTMTRDTSISTAYMELSR-(Ile-13C6,15N) is the 13C and 15N labeled isotope of VTMTRDTSISTAYMELSR.
    VTMTRDTSISTAYMELSR-(Ile-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N)
  • HY-107370S
    Atomoxetine-d7
    Atomoxetine-d7 (Tomoxetine-d7) is deuterium labeled Atomoxetine. Atomoxetine (Tomoxetine) is a selective noradrenaline reuptake inhibitor with Ki values of 5, 77 and 1451 nM for norepinephrine (NE), serotonin (5-HT) and dopamine (DA) transporters, respectively. Atomoxetine (Tomoxetine) increases of DAEX and NEEX in the PFC and enhances catecholaminergic neurotransmission. Atomoxetine (Tomoxetine) is a potent Na+ channels (VGSCs) blocker. Atomoxetine (Tomoxetine) can be used for attention-deficit hyperactivity disorder (ADHD) research.
    Atomoxetine-d<sub>7</sub>
  • HY-B0109S
    Dorzolamide-d5
    Dorzolamide-d5 is the deuterium labeled Dorzolamide. Dorzolamide (L671152) is a potent carbonic anhydrase II inhibitor, with IC50 values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. Dorzolamide possesses anti-tumor activity.
    Dorzolamide-d<sub>5</sub>
  • HY-19436S
    Solabegron-d8
    Solabegron-d8 (GW 427353-d8) is deuterium labeled Solabegron. Solabegron (GW 427353) is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM. Solabegron (GW 427353) is being developed for the treatment of overactive bladder and irritable bowel syndrome.
    Solabegron-d<sub>8</sub>
  • HY-B1971S1
    Deltamethrin-d6
    Deltamethrin-d6 (Decamethrin-d6) is deuterium labeled Deltamethrin. Deltamethrin (Decamethrin) is an orally active synthetic pyrethroid insecticide. Deltamethrin induces oxidative stress and results in inflammation and apoptosis via inhibiting Nrf2/HO-1 pathway. Deltamethrin has an anticancer effect by inducing apoptosis. Deltamethrin can be used extensively in pest control.
    Deltamethrin-d<sub>6</sub>
  • HY-B1449S12
    Uridine-d12
    Uridine-d12 (β-Uridine-d12) is the deuterium labeled Uridine (HY-B1449). Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond.
    Uridine-d<sub>12</sub>
  • HY-W719074
    Sulfisomidin-d4
    Sulfisomidin-d4 (Sulfaisodimidine-d4) is deuterium labeled Sulfisomidin. Sulfisomidin (Sulfaisodimidine) is an orally active short-acting sulfonamide antibacterial. Sulfisomidin can be used for the research of lower urinary tract infections.
    Sulfisomidin-d<sub>4</sub>
  • HY-W779021
    Adenosine-15N
    Adenosine-15N (Adenine riboside-15N) is 15N labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
    Adenosine-<sup>15</sup>N
  • HY-W007102S
    4-Methoxy-N,N-dimethylaniline-d2
    4-Methoxy-N,N-dimethylaniline-d2 is the deuterium labeled 4-Methoxy-N,N-dimethylaniline (HY-W007102).
    4-Methoxy-N,N-dimethylaniline-d<sub>2</sub>
  • HY-W014423S1
    L-Histidine-13C6,15N3,d5 hydrochloride hydrate
    L-Histidine-13C6,15N3,d5 hydrochloride hydrate is the deuterium, 13C-, and 15-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable.
    L-Histidine-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>3</sub>,d<sub>5</sub> hydrochloride hydrate
  • HY-W654195
    3-Hydroxyfluorene-d9
    3-Hydroxyfluorene-d9 is deuterium labeled 3-Hydroxyfluorene.
    3-Hydroxyfluorene-d<sub>9</sub>
  • HY-130239S
    14(S)-HDHA-d5
    14(S)-HDHA-d5 (14(S)-HDoHE-d5) is deuterium labeled 14(S)-HDHA. 14(S)-HDHA (14(S)-HDoHE) is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway.
    14(S)-HDHA-d<sub>5</sub>
  • HY-132523S
    Menaquinone 4-d7 2,3-Epoxide
    Menaquinone 4-d7 2,3-Epoxide is the deuterium labeled Menaquinone 4 2,3-Epoxide.
    Menaquinone 4-d<sub>7</sub> 2,3-Epoxide
  • HY-174394S
    CYP51-IN-25
    		Inhibitor
    CYP51-IN-25 is a orally active broad spectrum antifungal agent with the MIC80 of 0.00625-0.05 μg/mL. is a CYP51-IN-25 is a deuterated compound with antibiotic properties. CYP51-IN-25 can inhibit the fungal CYP51 enzyme, block ergosterol synthesis, and disrupt cell membrane integrity. CYP51-IN-25 can be used for research on fungal infections.
    CYP51-IN-25
  • HY-126474S
    MitoB-d15 bromide
    MitoB-d15 (bromide) is deuterium labeled MitoB (bromide). MitoB bromide is an exomarker of mitochondrial hydrogen peroxide. MitoB bromide is a mitochondria-targeted ratiometric probe, and can be used to measure levels of one major ROS, hydrogen peroxide, within living animals.
    MitoB-d<sub>15</sub> bromide
  • HY-165648S
    PtdIns-(1-palmitoyl-d9, 2-palmitoyl) sodium salt
    PtdIns-(1-palmitoyl-d9, 2-palmitoyl) (DPPI-d9) sodium salt is deuterium labeled PtdIns-(1-palmitoyl, 2-palmitoyl) (sodium salt).
    PtdIns-(1-palmitoyl-d<sub>9</sub>, 2-palmitoyl) sodium salt
  • HY-13570CS
    Betamethasone 21-phosphate-d5
    Betamethasone 21-phosphate-d5 is the deuterium labeled Betamethasone disodium phosphate. Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a kind of corticosteroid, which is commonly used in the intralesional research of keloids.
    Betamethasone 21-phosphate-d<sub>5</sub>
  • HY-B0493S
    Niflumic Acid-d5
    Niflumic Acid-d5 is the deuterium labeled Niflumic acid. Niflumic acid, a Ca2+-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
    Niflumic Acid-d<sub>5</sub>
  • HY-167597S
    C18:0-d7 GD1b Ceramide (d18:1/18:0-d7)
    C18:0-d7 GD1b Ceramide (d18:1/18:0-d7) is deuterium labeled C18:0 GD1b Ceramide (d18:1/18:0).
    C18:0-d<sub>7</sub> GD1b Ceramide (d18:1/18:0-d<sub>7</sub>)
  • HY-15790S
    Elobixibat-d5
    Elobixibat-d5 is the deuterium labeled Elobixibat (HY-15790). Elobixibat (A 3309; AZD 7806) is orally active, bile acid transporter (IBAT) inhibitor with IC50 values ??of 0.53 nM (human IBAT), 0.13 nM (mouse IBAT), and 5.8 nM (canine IBAT). Elobixibat can lower LDL cholesterol, increase serum GLP-1, promote colonic motility, and has the potential to treat metabolic syndrome. Elobixibat can be used in the study of chronic functional constipation (CIC), dyslipidemia, non-alcoholic hepatitis, and liver tumors in the elderly.
    Elobixibat-d<sub>5</sub>