Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (9979):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-142165S

(R)-Norverapamil-d₆ hydrochloride
(R)-Norverapamil-d₆ (hydrochloride) is deuterium labeled (R)-Norverapamil.

HY-W766807

rac-1,2-Dilinoleoyl-3-chloropropanediol-d₅
rac-1,2-Dilinoleoyl-3-chloropropanediol-d₅ (1,2-Dilinoleoyl-3-chloropropanediol-d₅) is deuterium labeled rac-1,2-Dilinoleoyl-3-chloropropanediol.

HY-B0083S1

Leflunomide-¹³C₆
Leflunomide-¹³C₆ (HWA486-¹³C₆) is ¹³C labeled Leflunomide. Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent.

HY-66005S5

Acetaminophen-d₅
Acetaminophen-d₅ is deuterated-labeled Acetaminophen (HY-66005). Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC₅₀ of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.

HY-W716728

3-Hydroxy-3-(3-hydroxyphenyl-2,4,5,6-d₄)propanoic acid
3-Hydroxy-3-(3-hydroxyphenyl-2,4,5,6-d₄)propanoic acid is deuterium labeled 3-Hydroxy-3-(3-hydroxyphenyl-2,4,5,6)propanoic acid.

HY-144386S

N-Desmethyl L-ergothioneine methyl ester-d₆
N-Desmethyl L-ergothioneine methyl ester-d₆ is the deuterium labeled N-Desmethyl L-ergothioneine methyl ester.

HY-W653916

8-Hydroxy-2'-deoxyguanosine-¹³C,¹⁵N₂
8-Hydroxy-2'-deoxyguanosine-¹³C,¹⁵N₂ is ¹³C and ¹⁵N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.

HY-132319S

(-)-Corey lactone diol-heptyldioxolane-d15
(-)-Corey lactone diol-heptyldioxolane-d₁₅ is the deuterium labeled (-)-Corey lactone diol-heptyldioxolane.

HY-B1395S

Mecamylamine-d₃ hydrochloride
Mecamylamine-d₃ hydrochloride is the deuterium labeled Mecamylamine hydrochloride. Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist that can treat various neuropsychiatric disorders. Mecamylamine hydrochloride is originally used as a ganglionic blocker in treating hypertension. Mecamylamine hydrochloride can easily crosses the blood-brain barrier.

HY-B1490AS

Imipramine-d₆
Imipramine-d₆ is the deuterium labeled Imipramine hydrochloride. Imipramine is an orally active tertiary amine tricyclic antidepressant. Imipramine is a Fascin1 inhibitor with antitumor activities. Imipramine also inhibits serotonin transporter with an IC₅₀ value of 32 nM. Imipramine stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis. Imipramine shows neuroprotective and immunomodulatory effects.

HY-150679S

Remdesivir-¹³C₆
Remdesivir-¹³C₆ is the ¹³C labeled Remdesivir.

HY-116776S

Hexadecatetraenoic acid-d₅
Hexadecatetraenoic acid-d₅ is deuterium labeled Hexadecatetraenoic acid. Hexadecatetraenoic acid is an unsaturated fatty acid that can be isolated from sardine oil.

HY-Y1169S2

Fmoc-Asp(OtBu)-OH-d₃
Fmoc-Asp(OtBu)-OH-d₃ (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d₃) is deuterium labeled Fmoc-Asp(OtBu)-OH. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis.

HY-W778144

O,O-Diethyl Thiophosphate-¹³C₄ ammonium
O,O-Diethyl Thiophosphate-¹³C₄ (ammonium) is ¹³C labeled O,O-Diethyl Thiophosphate (ammonium).

HY-132484S

4-Hydroxy Propafenone-d₅ hydrochloride
4-Hydroxy Propafenone-d₅ (hydrochloride) is the deuterium labeled 4-Hydroxy Propafenone hydrochloride.

HY-14779S3

Riociguat-d₃
Riociguat-d₃ (BAY 632521-d₃) is deuterium labeled Riociguat. Riociguat is an oral stimulator of soluble guanylate cyclase (sGC) used in the treatment of pulmonary hypertension.

HY-17402S1

Nisoldipine-d₄
Nisoldipine-d₄ (BAY-k 5552-d₄) is the deuterium labeled Nisoldipine. Nisoldipine(BAY-k 5552) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC₅₀ of 10 nM.

HY-N0230S5

β-Alanine-¹³C
β-Alanine-¹³C (2-Carboxyethylamine-¹³C) is ¹³C labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.

HY-W150287S

2,2'-(1,4-Phenylene)bis-4H-3,1-benzoxazin-4-one-d₄
2,2'-(1,4-Phenylene)bis-4H-3,1-benzoxazin-4-one-d₄ (4H-3,1-Benzoxazin-4-one, 2,2'-(1,4-phenylene)bis-d₄) is deuterium labeled 2,2'-(1,4-Phenylene)bis-4H-3,1-benzoxazin-4-one.

HY-13331S1

Clascoterone-d₆
Clascoterone-d₆ (Cortexolone 17 alpha-propionate-d₆) is deuterium labeled Clascoterone. Clascoterone (Cortexolone 17 alpha-propionate;Cortexolone 17α-propionate;CB-03-01) is a new topical and peripherally selective androgen antagonist.

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