2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9979):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-141629S2
    N-Palmitoyl-D-sphingomyelin-d9
    N-Palmitoyl-D-sphingomyelin-d9 (Sphingomyelin 16:0-d9) is deuterium labeled N-Palmitoyl-D-sphingomyelin. N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles.
    N-Palmitoyl-D-sphingomyelin-d<sub>9</sub>
  • HY-113037AS
    Farnesyl pyrophosphate-d6
    Farnesyl pyrophosphate-d6 (Farnesyl diphosphate-d6) is a deuterium labeled Farnesyl pyrophosphate (HY-113037B). Farnesyl pyrophosphate is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases.
    Farnesyl pyrophosphate-d<sub>6</sub>
  • HY-128393S1
    Trilinolein-13C54
    Trilinolein-13C54 is the 13C-labeled Trilinolein (HY-128393). Trilinolein is an orally active triglyceride that inhibits the PI3K/Akt, Ras/MEK/ERK signaling pathways, and MMP-2. Trilinolein can reduce oxidative stress, induce apoptosis, and inhibit cell migration. Trilinolein can be used in the research fields of cardiovascular disease, cerebrovascular disease (such as cerebral ischemia), and non-small cell lung cancer.
    Trilinolein-<sup>13</sup>C<sub>54</sub>
  • HY-W014901S1
    Bisphenol F-13C12
    Bisphenol F-13C12 is the 13C labeled Bisphenol F (HY-W014901). Bisphenol F is an orally active endocrine disruptor. Bisphenol F promotes ROS generation, upregulates p-AKT/p-GSK3β, and induces Apoptosis. Bisphenol F interferes with glucose metabolism, affects neurodevelopment and reproductive function. Bisphenol F reduces social novelty preference in mouse offspring. Bisphenol F can be used in bone, blood, and fat-related studies. Bisphenol F is used as a substitute for Bisphenol A (HY-18260).
    Bisphenol F-<sup>13</sup>C<sub>12</sub>
  • HY-W099489S
    Potassium O-pentyl carbonodithioate-d5
    Potassium O-pentyl carbonodithioate-d5 (Potassium amylxanthate-d5) is a deuterium labeled Potassium O-pentyl carbonodithioate (HY-W099489).
    Potassium O-pentyl carbonodithioate-d<sub>5</sub>
  • HY-W743781
    N-Nitrosonornicotine-d4
    N-Nitrosonornicotine-d4 ((2S)-N'-Nitrosonornicotine-d4) is deuterium labeled N-Nitrosonornicotine. N-Nitrosonornicotine is a tobacco-specific nitrosamine that has carcinogenic and mutagenic activity, and it can induce micronuclei in C3A cells. N-Nitrosonornicotine can form DNA adducts.
    N-Nitrosonornicotine-d<sub>4</sub>
  • HY-W701859
    3-Chloro-2-(stearoyloxy)propyl-1,1,2,3,3-d5 oleate
    3-Chloro-2-(stearoyloxy)propyl-1,1,2,3,3-d5 oleate (1-Oleoyl-2-Stearoyl-3-chloropropanediol-d5) is deuterium labeled 3-Chloro-2-(stearoyloxy)propyl-1,1,2,3,3 oleate.
    3-Chloro-2-(stearoyloxy)propyl-1,1,2,3,3-d<sub>5</sub> oleate
  • HY-W011280S
    (S)-2-(2-(1H-Indol-3-yl)acetamido)-3-phenylpropanoic acid-d4
    (S)-2-(2-(1H-Indol-3-yl)acetamido)-3-phenylpropanoic acid-d4 is deuterium labeled (S)-2-(2-(1H-Indol-3-yl)acetamido)-3-phenylpropanoic acid. (S)-2-(2-(1H-Indol-3-yl)acetamido)-3-phenylpropanoic acid is a phenylalanine derivative.
    (S)-2-(2-(1H-Indol-3-yl)acetamido)-3-phenylpropanoic acid-d<sub>4</sub>
  • HY-B1234S
    Octinoxate-13C,d3
    Octinoxate-13C,d3 is the deuterium labeled Octinoxate (HY-W245806). Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo.
    Octinoxate-<sup>13</sup>C,d<sub>3</sub>
  • HY-W725480
    Carfentrazon-ethyl-d5
    Carfentrazon-ethyl-d5 is the deuterium labeled Carfentrazon-ethyl-d5 (HY-W725480).
    Carfentrazon-ethyl-d<sub>5</sub>
  • HY-107405S
    TC-N 1752-d5
    TC-N 1752-d5 is deuterium-labeled TC-N 1752 (HY-107405).
    TC-N 1752-d<sub>5</sub>
  • HY-135035S
    Decanoyl-L-carnitine-d3
    Decanoyl-L-carnitine-d3 ((-)-Decanoylcarnitine-d3) is deuterium labeled Decanoyl-L-carnitine. Decanoyl-L-carnitine has stimulatory effect on the formation of desaturated fatty acid metabolites from both [1-14C]-22:4 (n-6) and [1-14C]-22:5 (n-3).
    Decanoyl-L-carnitine-d<sub>3</sub>
  • HY-141856S
    Acrolein 2,4-dinitrophenylhydrazone-3,5,6-d3
    Acrolein 2,4-dinitrophenylhydrazone-3,5,6-d3 is the deuterium labeled Acrolein 2,4-dinitrophenylhydrazone-3,5,6.
    Acrolein 2,4-dinitrophenylhydrazone-3,5,6-d<sub>3</sub>
  • HY-W009140S
    2,4,6-Tribromophenol-d2
    		99.93%
    2,4,6-Tribromophenol-d2 is the deuterium labeled 2,4,6-Tribromophenol.
    2,4,6-Tribromophenol-d<sub>2</sub>
  • HY-132466S
    Hydroxy Torsemide-d7
    Hydroxy Torsemide-d7 is the deuterium labeled Hydroxy Torsemide.
    Hydroxy Torsemide-d<sub>7</sub>
  • HY-10405S
    Pamapimod-d4
    Pamapimod-d4 (Ro4402257-d4) is the deuterium labeled Pamapimod. Pamapimod (Ro4402257) is a potent, selective and orally active p38 MAPK inhibitor with IC50s of 14 nM and 480 nM and Kis of 1.3 nM and 120 nM for p38α and p38β, respectively. Pamapimod has no activity against p38δ or p38γ isoforms. Pamapimod has the potential for rheumatoid arthritis and other autoimmune diseases treatment.
    Pamapimod-d<sub>4</sub>
  • HY-B0071S2
    Granisetron-d6 (Standard)
    Granisetron-d6 (BRL 43694-d6) is deuterium labeled Granisetron. Granisetron (BRL 43694) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.
    Granisetron-d<sub>6</sub> (Standard)
  • HY-14538S2
    Haloperidol-d4 N-Oxide
    Haloperidol-d4 N-Oxide is the deuterium labeled Haloperidol. Haloperidol is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic.
    Haloperidol-d<sub>4</sub> N-Oxide
  • HY-W011683S7
    2'-Deoxyadenosine monohydrate-15N5
    2'-Deoxyadenosine monohydrate-15N5 is the 15N labeled 2'-Deoxyadenosine monohydrate (HY-W011683). 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer.
    2'-Deoxyadenosine monohydrate-<sup>15</sup>N<sub>5</sub>
  • HY-B1252AS
    Cefalonium-d4 hydrate
    Cefalonium-d4 (hydrate) is the deuterium labeled Cefalonium (hydrate)(HY-B1252A).Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci.
    Cefalonium-d<sub>4</sub> hydrate