2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9894):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W767656
    Dropropizine-d4
    Dropropizine-d4 ((±)-Dropropizine-d4) is deuterium labeled Dropropizine. Dropropizine ((±)-Dropropizine) belongs to the phenylpiperazine group of organic compounds. Dropropizine is a peripheral antitussive agent that acts by inhibiting cough reflex through its action on the peripheral receptors and their afferent conductors .
    Dropropizine-d<sub>4</sub>
  • HY-108316S
    Sulthiame-d4
    Sulthiame-d4 is the deuterium labeled Sultiame. Sultiame is a carbonic anhydrase inhibitor, widely used as an antiepileptic agent.
    Sulthiame-d<sub>4</sub>
  • HY-W008614S1
    Lansoprazole sulfone-13C6
    Lansoprazole sulfone-13C6 (AG-1813-13C6) is 13C labeled Lansoprazole sulfone. Lansoprazole sulfone (AG-1813) is an orally active and selective inhibitor of H+, K+-ATPase. Lansoprazole sulfone can significantly stimulates gastric acid secretion by inhibiting H+, K+-ATPase. Lansoprazole sulfone has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease.
    Lansoprazole sulfone-<sup>13</sup>C<sub>6</sub>
  • HY-W654319
    Tri-p-tolyl phosphate-d21
    Tri-p-tolyl phosphate-d21 is the deuterium labeled Tri-p-tolyl phosphate.
    Tri-p-tolyl phosphate-d<sub>21</sub>
  • HY-B0224S
    Chlorothiazide-13C,15N2
    Chlorothiazide-13C,15N2 is the 13C and 15N labeled Chlorothiazide. Chlorothiazide is an orally active diuretic and anti-hypertensive agent.
    Chlorothiazide-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-13619S
    Efaproxiral-d6
    Efaproxiral-d6 is the deuterium labeled Efaproxiral. Efaproxiral (RSR13) is a haemoglobin (Hb) synthetic allosteric modifier, decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy.
    Efaproxiral-d<sub>6</sub>
  • HY-17492S3
    Zafirlukast-d6
    Zafirlukast-d6 is deuterated labeled Zafirlukast (HY-17492). Zafirlukast (ICI 204219) is a potent orally active leukotriene D4 (LTD4) receptor antagonist. Zafirlukast shows anti-asthmatic, anti-inflammatory and anti-bacterial effects.
    Zafirlukast-d<sub>6</sub>
  • HY-W653853
    Ritonavir-13C3
    Ritonavir-13C3 is 13C labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM.
    Ritonavir-<sup>13</sup>C<sub>3</sub>
  • HY-W744264
    Flumazenil-d5
    Flumazenil-d5 is deuterium labeled Flumazenil.
    Flumazenil-d<sub>5</sub>
  • HY-B1811S1
    Vasopressin-d5
    Vasopressin-d5 is anIsotope-labeled compound of Vasopressin. Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of the corticotropin-releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors.
    Vasopressin-d<sub>5</sub>
  • HY-P0119S
    Lixisenatide (Leu-13C6,15N) TFA
    Lixisenatide (Leu-13C6,15N) TFA is the 13C- and 15N-labeled Lixisenatide (HY-P0119). Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist. Lixisenatide inhibits the inflammatory response through down regulation of pro-inflammatory cytokines, and suppresses of the Akt-MEK1/2 signaling pathway. Lixisenatide can inhibit oxidative stress, mitochondrial dysfunction and apoptosis. Lixisenatide can be used for the researches of inflammation, metabolic disease, neurological disease and cardiovascular disease, such as rheumatoid arthritis, diabetes, Alzheimer's disease and atherosclerosis.
    Lixisenatide (Leu-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N) TFA
  • HY-141722S
    Carboxyphosphamide-d4
    Carboxyphosphamide-d4 is the deuterium labeled Carboxyphosphamide.
    Carboxyphosphamide-d<sub>4</sub>
  • HY-B0148S
    Risedronic acid-d4
    Risedronic acid-d4 (Risedronate-d4) is the deuterium labeled Risedronic acid (HY-B0148). Risedronic acid (Risedronate) is a bisphosphonate and potent antiresorptive agent. Risedronic acid induces Apoptosis. Risedronic acid inhibits the transfer of farnesyl pyrophosphate groups to parasite proteins. Risedronic acid inhibits osteoclast-mediated bone resorption and alters bone metabolism. Risedronic acid inhibits blood-stage Plasmodium falciparum (IC50 of 20.3 μM).
    Risedronic acid-d<sub>4</sub>
  • HY-N0095S
    (S)-10-Hydroxycamptothecin-d5
    (S)-10-Hydroxycamptothecin-d5 (10-HCPT-d5) is the deuterium labeled (S)-10-Hydroxycamptothecin. (S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor. (S)-10-Hydroxycamptothecin exhibits a remarkable apoptosis-inducing effect. (S)-10-Hydroxycamptothecin has the potential for hepatoma, gastric carcinoma, colon cancer and leukaemia research.
    (S)-10-Hydroxycamptothecin-d5
  • HY-W714702S
    2-((2,6-Dimethylphenyl)(2-(methoxy-d3)ethyl)amino)-2-oxoacetic acid
    2-((2,6-Dimethylphenyl)(2-(methoxy-d3)ethyl)amino)-2-oxoacetic acid is deuterium labeled 2-((2,6-Dimethylphenyl)(2-methoxyethyl)amino)-2-oxoacetic acid.
    2-((2,6-Dimethylphenyl)(2-(methoxy-d<sub>3</sub>)ethyl)amino)-2-oxoacetic acid
  • HY-B0696S1
    Tiagabine-d4
    Tiagabine-d4 (NO050328-d4) is deuterium labeled Tiagabine. Tiagabine (NO050328) is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC50s of 67, 446 and 182 nM for [3H]GABA uptake in Synaptosomes, Neurons and Glia, respectively.
    Tiagabine-d<sub>4</sub>
  • HY-12769S2
    Mebeverine acid-d3
    Mebeverine acid-d3 (Mebeverine metabolite Mebeverine acid-d3) is deuterium labeled Mebeverine acid. Mebeverine acid (Mebeverine metabolite Mebeverine acid) is a secondary metabolite of Mebeverine. Mebeverine is an antispasmodic agent. Mebeverine acid is a valuable marker of oral exposure to Mebeverine.
    Mebeverine acid-d<sub>3</sub>
  • HY-17368S1
    (Rac)-Rivastigmine-d6
    (Rac)-Rivastigmine-d6 is a labelled racemic Rivastigmine. Rivastigmine (ENA 713 free base) is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC50s of 0.037 μM , 4.15 μM, respectively. Rivastigmine can pass the blood brain barrier (BBB). Rivastigmine is a parasympathomimetic or cholinergic agent used for the research of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease.
    (Rac)-Rivastigmine-d<sub>6</sub>
  • HY-15746S1
    (rac)-Dobutamine-d6 hydrochloride
    (rac)-Dobutamine-d6 (hydrochloride) is a labelled racemic Dobutamine hydrochloride. Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion.
    (rac)-Dobutamine-d<sub>6</sub> hydrochloride
  • HY-N0221S2
    Daurisoline-d11
    Daurisoline-d11 is the deuterium labeled Daurisoline (HY-N0221). Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer.
    Daurisoline-d<sub>11</sub>