Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (9979):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-B0478AS

Trazodone-d₆ hydrochloride		99.62%
Trazodone-d₆ (hydrochloride) is the deuterium labeled Trazodone hydrochloride.

HY-134938S

7-Hydroxywarfarin-d₅		98.05%
7-Hydroxywarfarin-d₅ is the deuterium labeled 7-Hydroxywarfarin.

HY-10882S

Clotrimazole-d₅		99.47%
Clotrimazole-d₅ is the deuterium labeled Clotrimazole. Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity.

HY-W018004S

L-Homocitrulline-d₃		98.90%
L-Homocitrulline-d₃ is the deuterium labeled L-Homocitrulline. L-Homocitrulline is metabolized to homoarginine through homoargininosuccinate via the urea cycle pathway and its metabolic abnormality could lead to Lysinuric Protein Intolerance (LPI).

HY-I0983S

1,1,3,3-Tetramethylurea-d₁₂		98.17%
1,1,3,3-Tetramethylurea-d₁₂ is the deuterium labeled 1,1,3,3-Tetramethylurea.

HY-B1449S11

Uridine-¹³C₉		99.00%
Uridine-¹³C₉ (β-Uridine-¹³C₉) is a ¹³C9-labeled form of Uridine (HY-B1449). Uridine (β-Uridine) is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond.

HY-Y0264S

4-Hydroxybenzoic acid-¹³C₆		99.9%
4-Hydroxybenzoic acid-¹³C6 is the ¹³C labeled isotope of 4-Hydroxybenzoic acid-¹³C6.4-Hydroxybenzoic acid is a phenolic derivative of benzoic acid, which can inhibit most Gram-positive bacteria and some Gram-negative bacteria with an IC50 value of 160 μg/mL.

HY-13904S

Flumatinib-d₃		99.9%
Flumatinib-d₃ is deuterium labeled Flumatinib. Flumatinib (HHGV678) is an orally available, selective inhibitor of Bcr-Abl. Flumatinib inhibits c-Abl, PDGFRβ and c-Kit with IC₅₀s of 1.2 nM, 307.6 nM and 665.5 nM, respectively.

HY-W012382S

N-Acetyl-L-tyrosine-d₃		98.43%
N-Acetyl-L-tyrosine-d₃ is the deuterated form of N-Acetyl-L-tyrosine (HY-W012382). N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level reactive oxygen species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1 pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer.

HY-107372S4

Uridine triphosphate-¹⁵N₂ dilithium		98.0%
Uridine triphosphate-¹⁵N₂ (UTP-¹⁵N₂ dilithium; Uridine 5'-triphosphate-¹⁵N₂) dilithium is ¹⁵N labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.

HY-Y0747S

Iodobenzene-d₅
Iodobenzene-d₅ is the deuterium labeled 1-Iodobenzene. Iodobenzene can undergo Ullmann coupling reaction on copper catalyst to generate biphenyl. Iodobenzene can undergo Suzuki reaction with phenylboronic acid to generate biphenyl.

HY-45842S

4,6-Dichloro-N-methylpyridazine-3-carboxamide-d₃
4,6-Dichloro-N-methylpyridazine-3-carboxamide-d₃ is the deuterium labeled 4,6-Dichloro-N-methylpyridazine-3-carboxamide (HY-45842).

HY-W014633S

4-(Trifluoromethoxy)benzoic acid-d₄		99.60%
4-(Trifluoromethoxy)benzoic acid-d₄ is the deuterium labeled 4-(Trifluoromethoxy)benzoic acid.

HY-Y0304S

Dibutyl phthalate-3,4,5,6-d₄		99.80%
Dibutyl phthalate-3,4,5,6-d₄ is the deuterium labeled Dibutyl phthalate. Dibutyl phthalate is a commonly used plasticizer commonly found in some food packaging materials, personal care products, and the coating of oral medications. May cause toxicity and adverse neurobehavioral effects.

HY-W023144S

Tris(1-chloro-2-propyl) phosphate-d₁₈
Tris(1-chloro-2-propyl) phosphate-d₁₈ (Tris(1-chloropropan-2-yl) phosphate-d₁₈) is a deuterium labeled compound.

HY-17422S1

Acyclovir-d₄		98.66%
Acyclovir-d₄ is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC₅₀ of 0.85 μM), HSV-2 (IC₅₀ of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia.

HY-B0234S4

Estrone-d₂-1
Estrone-d₂-1 is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells.

HY-B0129S

Aztreonam-d₆		99.29%
Aztreonam-d₆ is deuterium labeled Aztreonam. Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3).

HY-18569S1

3-Indoleacetic acid-d₄		99.40%
3-Indoleacetic acid-d₄ (Indole-3-acetic acid-d₄; 3-IAA-d₄) is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.

HY-N0470S4

L-Lysine-d₈ hydrochloride		99.88%
L-Lysine-d₈ (hydrochloride) is the deuterium labeled L-Lysine hydrochloride. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health.

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