2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9621):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-13637S
    Ganciclovir-d5
    		98.32%
    Ganciclovir-d5 is the deuterium labeled Ganciclovir. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1).
    Ganciclovir-d<sub>5</sub>
  • HY-W002112S
    (±)-Nornicotine-d4
    		98.0%
    (±)-Nornicotine-d4 is the deuterium labeled (±)-Nornicotine (HY-W002112). (±)-Nornicotine is a major metabolite of Nicotine. (±)-Nornicotine is a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. (±)-Nornicotine disrupts β-catenin and ZO-1, and induces F-actin depolymerization. (±)-Nornicotine supports self-administration behavior. (±)-Nornicotine can be used in the research of atherosclerosis, Alzheimer's disease, and schizophrenia.
    (±)-Nornicotine-d<sub>4</sub>
  • HY-N1201S
    Apigenin-d5
    		98.90%
    Apigenin-d5 is a deuterated labeled Apigenin. Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM.
    Apigenin-d<sub>5</sub>
  • HY-B1776AS
    Spermidine-d8 hydrochloride
    Spermidine-d8 (hydrochloride)e is the deuterium labeled Spermidine trihydrochloride. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents.
    Spermidine-d<sub>8</sub> hydrochloride
  • HY-W010042S3
    L-Glucose-13C6
    		99.43%
    L-Glucose-13C6 (L-(-)-Glucose-13C6) is C13-labeled L-Glucose. L-Glucose is an enantiomer of D-glucose. L-Glucose enhances food intake.
    L-Glucose-<sup>13</sup>C<sub>6</sub>
  • HY-14233S
    Omecamtiv mecarbil-d8
    		99.57%
    Omecamtiv mecarbil-d8 is the deuterium labeled Omecamtiv mecarbil. Omecamtiv mecarbil (CK-1827452) is a selective cardiac myosin activator.
    Omecamtiv mecarbil-d<sub>8</sub>
  • HY-18206S
    Lisinopril-d5
    Lisinopril-d5 is the deuterium labeled Lisinopril. Lisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.
    Lisinopril-d<sub>5</sub>
  • HY-N7403S
    N-(3-Phenylpropionyl)glycine-d2
    		99.64%
    N-(3-Phenylpropionyl)glycine-d2 is the deuterium labeled N-(3-Phenylpropionyl)glycine.
    N-(3-Phenylpropionyl)glycine-d<sub>2</sub>
  • HY-B0317S1
    Amlodipine-d4
    		98.46%
    Amlodipine-d4 is a deuterium labeled Amlodipine (HY-B0317). Amlodipine, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine can be used for the research of high blood pressure and cancer.
    Amlodipine-d<sub>4</sub>
  • HY-W653930
    4,4'-Sulfonyldiphenol-13C12
    4,4'-Sulfonyldiphenol-13C12 (Bisphenol S-13C12) is 13C labeled 4,4'-Sulfonyldiphenol. 4,4'-Sulfonyldiphenol (Bisphenol S; Bis(4-hydroxyphenyl) sulfone) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    4,4'-Sulfonyldiphenol-<sup>13</sup>C<sub>12</sub>
  • HY-Y0682S
    Ethylenediaminetetraacetic acid-d12
    		98.00%
    Ethylenediaminetetraacetic acid-d12 is the deuterium labeled Ethylenediaminetetraacetic acid. Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds.
    Ethylenediaminetetraacetic acid-d<sub>12</sub>
  • HY-Y1097S
    Monomethyl phthalate-d4
    Monomethyl phthalate-d4 (2-(Methoxycarbonyl)benzoic acid-d4) is the deuterium labeled Monomethyl phthalate. Monomethyl phthalate is a phthalate metabolite. Monomethyl phthalate acts as a urinary biomarker of phthalates exposure and can be used as a standard for the determination of thyroid cancer and benign nodule.
    Monomethyl phthalate-d<sub>4</sub>
  • HY-16973S
    Fluralaner-13C2,15N,d3
    		98.35%
    Fluralaner-13C2,15N,d3 is the deuterium, 13C-, and 15-labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
    Fluralaner-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N,d<sub>3</sub>
  • HY-128754S
    Monoolein-d5
    		99.94%
    Monoolein-d5 is the deuterium labeled Monoolein. Monoolein is an endogenous metabolite.
    Monoolein-d<sub>5</sub>
  • HY-13956S1
    Pioglitazone-d4 (alkyl)
    		98.55%
    Pioglitazone-d4 (alkyl) (U 72107-d4 (alkyl)) is the deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.
    Pioglitazone-d<sub>4</sub> (alkyl)
  • HY-W303130S
    Sinapic acid ethyl ester-d3
    Sinapic acid ethyl ester-d3 is a deuterium labeled sinapic acid ethyl ester.
    Sinapic acid ethyl ester-d<sub>3</sub>
  • HY-B0002S
    Ondansetron-d3 hydrochloride
    		98.78%
    Ondansetron-d3 (hydrochloride) is the deuterium labeled Ondansetron hydrochloride. Ondansetron hydrochloride (GR 38032 hydrochloride) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy.
    Ondansetron-d<sub>3</sub> hydrochloride
  • HY-Y0989S4
    Acetophenone-d3
    Acetophenone-d3 is the deuterium labeled Acetophenone. Acetophenone is an organic compound with simple structure.
    Acetophenone-d<sub>3</sub>
  • HY-158087S
    N-(1-Oxopentadecyl)glycine-d2
    N-(1-Oxopentadecyl)glycine-d2 is the deuterated labeled N-(1-Oxopentadecyl)glycine.
    N-(1-Oxopentadecyl)glycine-d<sub>2</sub>
  • HY-W778336
    Girard's Reagent P-d5
    		≥99.0%
    Girard's Reagent P-d5 is a deuterated labeled Girard's Reagent P-d5.
    Girard's Reagent P-d<sub>5</sub>