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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9980):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-133706S
    2-Nitrobenzaldehyde semicarbazone-13C,15N2
    98.02%
    2-Nitrobenzaldehyde semicarbazone-13C,15N2 is used for analysis of semicarbazide in the LC-MS/MS method.
    2-Nitrobenzaldehyde semicarbazone-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-143782S
    Enalaprilat-d5 maleate
    Enalaprilat-d5 (maleate) is the deuterium labeled Enalaprilat maleate.
    Enalaprilat-d<sub>5</sub> maleate
  • HY-W741978
    Dihydrocuscohygrine-d6
    Dihydrocuscohygrine-d6 is the deuterium labeled Dihydrocuscohygrine.
    Dihydrocuscohygrine-d<sub>6</sub>
  • HY-120927S
    Alvimopan metabolite-d5
    Alvimopan metabolite-d5 is the deuterium labeled Alvimopan Metabolite.
    Alvimopan metabolite-d<sub>5</sub>
  • HY-122141S
    Glycohyocholic acid-d4
    Glycohyocholic acid-d4 is the deuterium labeled Glycohyocholic acid (HY-122141). Glycohyocholic acid (GHCA) is a primary conjugated bile acid formed by the conjugation of Cholic acid (HY-N0324) and Glycine (HY-Y0966). Glycohyocholic acid can be used in the study of hepatitis C-related cirrhosis and diabetes mellitus.
    Glycohyocholic acid-d<sub>4</sub>
  • HY-113359AS1
    Uridine 5'-diphosphate-13C9 dilithium
    Uridine 5'-diphosphate-13C9 dilithium is 13C-labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y6 receptor agonist with an EC50 of 0.013 μM for human P2Y6 receptor.
    Uridine 5'-diphosphate-<sup>13</sup>C<sub>9</sub> dilithium
  • HY-153830S
    LacCer (d18:1/16:0)-d3
    LacCer (d18:1/16:0)-d3 (C16 Lactosylceramide (d18:1/16:0)-d3) is the deuterium labeled LacCer (d18:1/16:0) (HY-153830). LacCer (d18:1/16:0) is an endogenous bioactive sphingolipid that can form membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs). The levels of LacCer (d18:1/16:0) are elevated in the plasma of insulin-resistant cattle. In a mouse model of Niemann-Pick type C1 disease (a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder), the expression of LacCer (d18:1/16:0) is also upregulated. LacCer (d18:1/16:0) can be used in research on metabolic diseases and neurodegenerative diseases.
    LacCer (d18:1/16:0)-d<sub>3</sub>
  • HY-144233S
    N1-Acetyl triethylenetetramine-d8 trihydrochloride
    N1-Acetyl triethylenetetramine-d8 (trihydrochloride) is the deuterium labeled N1-Acetyl triethylenetetramine trihydrochloride.
    N1-Acetyl triethylenetetramine-d<sub>8</sub> trihydrochloride
  • HY-166909S
    1,4,5-Trichloronaphthalene-13C10
    1,4,5-Trichloronaphthalene-13C10 is 13C labeled 1,4,5-Trichloronaphthalene.
    1,4,5-Trichloronaphthalene-<sup>13</sup>C<sub>10</sub>
  • HY-N0067S2
    γ-Aminobutyric acid-4,4-d2
    γ-Aminobutyric acid-4,4-d2 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].
    γ-Aminobutyric acid-4,4-d<sub>2</sub>
  • HY-W704647
    1,2-Ethanediol, 1-(dihydrogen phosphate)-d4
    1,2-Ethanediol, 1-(dihydrogen phosphate)-d4 is the deuterium labeled 1,2-Ethanediol, 1-(dihydrogen phosphate) (HY-W587924).
    1,2-Ethanediol, 1-(dihydrogen phosphate)-d<sub>4</sub>
  • HY-113225S4
    Guanosine triphosphate-15N5,d14 dilithium
    98.4%
    Guanosine triphosphate-15N5,d14 (GTP-15N5,d14) dilithium is deuterium and 15N labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19.
    Guanosine triphosphate-<sup>15</sup>N<sub>5</sub>,d<sub>14</sub> dilithium
  • HY-W041195S
    3-Hydroxy-3-methylhexanoic acid-d5
    3-Hydroxy-3-methylhexanoic acid-d5 is the deuterium labeled 3-Hydroxy-3-methylhexanoic acid (HY-W041195). 3-Hydroxy-3-methylhexanoic acid is a fatty acid that is one of the metabolic products of leukocytes.
    3-Hydroxy-3-methylhexanoic acid-d<sub>5</sub>
  • HY-W040193S6
    DSPC-d13
    99.0%
    DSPC-d13 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system.
    DSPC-d<sub>13</sub>
  • HY-17380S
    (S)-Timolol-d9 maleate
    (S)-Timolol-d9 (maleate) is deuterium labeled (S)-Timolol (Maleate). (S)-Timolol Maleate (L-714,465 Maleate) is a non-cardioselective hydrophilic β-adrenoceptor blocker. (S)-Timolol Maleate is widely used as standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. (S)-Timolol Maleate can be used for hypertension, angina pectoris and myocardial infarction.
    (S)-Timolol-d<sub>9</sub> maleate
  • HY-18628S
    UMI-77-d4
    UMI-77-d4 is the deuterium labeled UMI-77. UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 μM). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members.
    UMI-77-d<sub>4</sub>
  • HY-146924S
    DL-Dipalmitoylphosphatidylcholine-d80
    99.0%
    16:0 (Rac)-PC-d80 is deuterium labeled 16:0 (Rac)-PC.
    DL-Dipalmitoylphosphatidylcholine-d<sub>80</sub>
  • HY-B1396S1
    Nefazodone-d6 dihydrochloride
    Nefazodone-d6 (dihydrochloride) is deuterium labeled Nefazodone (hydrochloride). Nefazodone hydrochloride (BMY-13754) is a potent and selective 5HT2A (Ki=5.8 nM) antagonist with moderate inhibition of 5-HT and noradrenaline uptake (IC50 of 290 and 300 nM, respectively). Nefazodone hydrochloride is a phenylpiperazine antidepressant with less alpha-adrenergic blocking activity.
    Nefazodone-d<sub>6</sub> dihydrochloride
  • HY-N0830S14
    Palmitic acid-d17
    Palmitic acid-d17 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells.
    Palmitic acid-d<sub>17</sub>
  • HY-Y0123S3
    DL-Tyrosine-d3
    DL-Tyrosine-d3 is the deuterium labeled DL-Tyrosine. DL-Tyrosine is an aromatic nonessential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is a precursor for several important neurotransmitters (epinephrine, norepinephrine, dopamine).
    DL-Tyrosine-d<sub>3</sub>