Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (9980):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-A0132S12

N-Acetyl-D-glucosamine-¹³C₆
N-Acetyl-D-glucosamine-¹³C₆ (N-Acetyl-2-amino-2-deoxy-D-glucose-¹³C₆) is the ¹³C labled N-Acetyl-D-glucosamine (HY-A0132). N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of glucose.

HY-135328AS

Norverapamil-d₇ hydrochloride		98.77%
Norverapamil-d₇ (hydrochloride) is a deuterium labeled Norverapamil. Norverapamil ((±)-Norverapamil), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.

HY-13771S1

Ursodeoxycholic acid-¹³C
Ursodeoxycholic acid-¹³C is the ¹³C labeled Ursodeoxycholic acid. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active.

HY-W705406

3-Carboxy Detomidine Methyl Ester-¹⁵N₂
3-Carboxy Detomidine Methyl Ester-¹⁵N₂ is the ¹⁵N labeled 3-Carboxy Detomidine Methyl Ester.

HY-W707562

FOY 251-d₄
FOY 251-d₄ is the deuterium labeled FOY 251 (HY-19727A). FOY 251, an anti-proteolytic active metabolite Camostate (HY-13512), acts as a proteinase inhibitor. FOY 251 inhibits SARS-CoV-2 infection in cells assay.

HY-W011683S3

2'-Deoxyadenosine monohydrate-5′-¹³C
2'-Deoxyadenosine monohydrate-5′-¹³C is the ¹³C labeled 2'-Deoxyadenosine monohydrate (HY-W011683). 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer.

HY-W710425

N-(Methyl-d₃)-5-nitroquinolin-6-amine
N-(Methyl-d₃)-5-nitroquinolin-6-amine is the deuterium labeled N-methyl-5-nitroquinolin-6-amine (HY-W334909).

HY-B0153AS

Ticlopidine-d₄ hydrochloride
Ticlopidine-d₄ (hydrochloride) is the deuterium labeled Ticlopidine hydrochloride. Ticlopidine hydrochloride is an adenosine diphosphate (ADP) receptor inhibitor against platelet aggregation with IC50 of ~2 μM.

HY-W097453S1

6-(Methylthio)purine-d₃
6-(Methylthio)purine₃ is the deuterium labeled 6-(Methylthio)purine.

HY-13632S1

Exemestane-¹³C₃
Exemestane-¹³C₃ is the ¹³C-labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research.

HY-B0648S1

Medroxyprogesterone-d₇
Medroxyprogesterone-d₇ is deuterium labeled Medroxyprogesterone.

HY-B0473S

Tetracaine-d₆ hydrochloride
Tetracaine-d₆ (hydrochloride) is the deuterium labeled Tetracaine hydrochloride.

HY-17509S

Deracoxib-d₃
Deracoxib-d₃ (SC 046-d₃; SC 59046-d₃) is the deuterium labeled Deracoxib (HY-17509). Deracoxib, an orally active COX-2 inhibitor, is a veterinary nonsteroidal anti-inflammatory agent used exclusively in dogs. Deracoxib inhibits the COX-2 enzyme to reduce the production of prostaglandins, effectively controlling pain and inflammation after canine soft tissue surgery. Deracoxib reduces the inhibition of COX-1 and lowers the risk of gastrointestinal side effects. Deracoxib induces tumor cell cycle arrest and apoptosis, and shows anti-tumor activity in canine osteosarcoma, breast tumors and bladder transitional cell carcinomas.

HY-W353946S

Mono-iso-Propyl Phthalate-3,4,5,6-d₄
Mono-iso-Propyl Phthalate-3,4,5,6-d₄ is the deuterium labeled Mono-iso-Propyl Phthalate.

HY-W778297

5,6-Diamino-4-thiouracil-¹³C₂
5,6-Diamino-4-thiouracil-¹³C₂ is the ¹³C-labeled 5,6-Diamino-4-thiouracil (HY-W740396).

HY-W777099

N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly[¹³C₂,¹⁵N]-OBzl
N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly[¹³C₂,¹⁵N]-OBzl is the ¹³C- and ¹⁵N-labeled N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly-OBzl.

HY-W743774

gamma-Cyhalothrin-(phenoxy-d₅)
gamma-Cyhalothrin-(phenoxy-d5₅) is a deuterated labeled gamma-Cyhalothrin-(phenoxy).

HY-W097055S

2-(2-Formamidothiazol-4-yl)acetic acid-¹³C,¹⁵N₂
2-(2-Formamidothiazol-4-yl)acetic acid-¹³C,¹⁵N₂ (2-Formamidothiazol-4-acetic acid-¹³C,¹⁵N₂) is the ¹³C- and ¹⁵N-labeled 2-(2-Formamidothiazol-4-yl)acetic acid (HY-W097055).

HY-33549S

DL-Metirosine-¹³C,d₃ hydrochloride
DL-Metirosine-¹³C,d₃ (hydrochloride) is deuterium labeled α-Methyl-p-tyrosine.

HY-W720448

VR23-d₈
VR23-d₈ is the deuterium labeled VR23 (HY-18741). VR23 is a small molecule that potently inhibits the activities of trypsin-like proteasomes (IC₅₀=1 nM), chymotrypsin-like proteasomes (IC₅₀=50-100 nM), and caspase-like proteasomes (IC₅₀=3 μM).

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