2. Signaling Pathways
  3. Others
  4. Insecticide

Insecticide

Insecticide

Insecticides refer to any toxic substances used to kill insects, which exert toxic effects on pests through different mechanisms, thereby achieving the purpose of controlling pest populations and protecting crops and human health. Insecticides have both chemical and biological origins and can be classified into organochlorine insecticides, organophosphorus insecticides, carbamate insecticides, and mineral insecticides based on their chemical properties. Insecticides interact with different target and non-target sites, including receptors, enzymes, and many other known and unknown molecules. Most insecticides are neurotoxicants that target the nervous system, but they can also affect other organs and body systems. Insecticides are metabolized through different metabolic pathways and often serve as biomarkers of exposure in the form of their parent compounds or metabolites. The toxicity of insecticides can be acute, subacute, or chronic, depending on the duration of exposure and the dose involved. Therefore, selecting sensitive, accurate, and validated biomarkers of exposure, effects, and susceptibility appears to be a challenging task.
Insecticides are widely used in agriculture, horticulture, forestry, gardening, homes, offices, and other fields[1][2].

Insecticide Related Products (334):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W013170
    MGK-264
    		≥98.0%
    MgK-264 (N-octylbicycloheptenedicarboximide) is a synergist enhancing the potency of pyrethroid ingredients. MgK-264 has no intrinsic pesticidal qualities itself.
    MGK-264
  • HY-130221
    (25S)-Δ7-Dafachronic acid
    (25S)-Δ7-Dafachronic acid is a ligand and activator of DAF-12 receptor. DAF-12 is a nuclear hormone receptor that regulates larval diapause, developmental age, and adult longevity in Caenorhabditis elegans.
    (25S)-Δ7-Dafachronic acid
  • HY-121263
    Dicyclanil
    		Inhibitor 99.77%
    Dicyclanil is an insect growth regulator compound with a similar chemical structure to cyromazine.
    Dicyclanil
  • HY-18598
    Chitinase-IN-1
    		98.04%
    Chitinase-IN-1 is an insecticide that can inhibit the activity of chitinase and N-acetylglucosaminidase. The inhibition percentages for glycosidase and N-acetylglucosaminidase at concentrations of 50 uM and 20 uM are 75% and 67%, respectively.
    Chitinase-IN-1
  • HY-B1973
    Diflubenzuron
    		98.70%
    Diflubenzuron is an insecticide with larvicidal and ovicidal activities. Diflubenzuron can inhibit the synthesis of chitin in insects, affect insect molting and lead to the death of insects.
    Diflubenzuron
  • HY-B1146R
    Denatonium benzoate (Standard)
    Denatonium (benzoate) (Standard) is the analytical standard of Denatonium (benzoate). This product is intended for research and analytical applications. Denatonium benzoate (THS-839) is the most bitter compound known, commonly used as an aversion agent (bitter agent) to prevent inappropriate ingestion, used in denatured alcohol, antifreeze, nail biting prevention, respirator mask fit testing , animal repellents, liquid soaps and shampoos.
    Denatonium benzoate (Standard)
  • HY-W014566
    4-Nitro-3-(trifluoromethyl)phenol
    		99.91%
    4-Nitro-3-(trifluoromethyl)phenol (TFM) is a piscicide that is toxic to lampreys (P. marinus) (LC50 values ??are 1.97-2.11 for cysts, 2.05-2.21 for fry, 1.6-2.45 for juveniles, and 1.6-1.63 for adults, respectively). 4-Nitro-3-(trifluoromethyl)phenol is also toxic to juvenile lake sturgeons (A. fulvescens) less than 100 mm, but is nontoxic to a variety of other fish species. 4-Nitro-3-(trifluoromethyl)phenol (50 μM) dissociates oxidative phosphorylation by 22% and 28% in isolated livers of lampreys and rainbow trout (O. mykiss), respectively. 4-Nitro-3-(trifluoromethyl)phenol can be used to control lamprey larval populations.
    4-Nitro-3-(trifluoromethyl)phenol
  • HY-117419A
    (±)-Lavandulyl acetate
    		≥98.0%
    (±)-Lavandulyl acetate can be isolated from the oil components of Lavandula angustifolia Mill.
    (±)-Lavandulyl acetate
  • HY-148964
    Thiotraniliprole
    Thiotraniliprole (HY366) is an ortho formamidobenzamide insecticide that can be used for the synthesis of insecticidal combinations. Thiotraniliprole has potential applications in the prevention of lepidoptera pests, coleoptera pests, ants, and termites.
    Thiotraniliprole
  • HY-133204
    Chlorfluazuron
    		98.89%
    Chlorfluazuron (IKI-7899) is a benzoylurea insecticide. Chlorfluazuron inhibts insect chitin and disrupts normal exuviation by inducing malformations, thereby preventing and controlling lepidopteran pests.
    Chlorfluazuron
  • HY-B0916
    Propoxur
    		99.43%
    Propoxur is a reversible, competitive, orally active AChE inhibitor that can cross the blood-brain barrier. Propoxur inhibits AChE activity to induce neurotoxicity, while promoting MMP-2 expression and enhancing tumor cell migration and invasion by inducing intracellular ROS generation and activating the ERK/Nrf2 signaling pathway. On the one hand, Propoxur inhibits AChE, leading to acetylcholine accumulation and causing neurological dysfunction; on the other hand, it promotes Nrf2 nuclear translocation through ROS-dependent ERK1/2 phosphorylation, and upregulates MMP-2 and other invasion-related proteins. Propoxur is also a carbamate insecticide used to combat turf, forestry, and household pests.
    Propoxur
  • HY-120425
    Ethiprole
    		≥98.0%
    Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity.
    Ethiprole
  • HY-118541
    RH-5849
    		99.35%
    RH-5849 is an orally active agonist for non-steroidal ecdysteroid, which inhibits the larval growth of Plodia inferpuncteila in a dose-dependent manner. RH-5849 exhibits molting hormone activity.
    RH-5849
  • HY-114502
    Chrysanthemic acid
    		99.10%
    Chrysanthemic acid (NSC 11779) is an organic compound that is associated with a variety of natural and synthetic insecticides for the prevention of insect-borne diseases, among others.
    Chrysanthemic acid
  • HY-W019334
    3,4-Dimethylpyrazole phosphate
    		≥98.0%
    3,4-Dimethylpyrazole phosphate is a nitrification inhibitor. 3,4-Dimethylpyrazole phosphate decreases gross soil autotrophic nitrification rates and reduces gross mineralization rates through feedback regulation. 3,4-Dimethylpyrazole phosphate can also reduce the risk of nitrate leaching and N losses due to denitrification and do not increase NH3 volatilization.
    3,4-Dimethylpyrazole phosphate
  • HY-W052234
    4-Fluorophenoxyacetic acid
    		99.70%
    4-Fluorophenoxyacetic acid is a herbicide and plant defense inducer. 4-Fluorophenoxyacetic can inhibit the heading of monocotyledonous weeds and induce their sterility. Additionally, 4-Fluorophenoxyacetic acid can induce the defense mechanism of cereals to suppress pest populations and increase the yield of field crops.
    4-Fluorophenoxyacetic acid
  • HY-118659
    Benzalphthalide
    		98.04%
    Benzalphthalide (3-Benzylidenephthalide), a phthalate compound, is an insecticide.
    Benzalphthalide
  • HY-W067479
    (E)-Cinnamamide
    		99.35%
    (E)-Cinnamamide, the less active isomer of Cinnamamide. Cinnamamide, a derivative of the plant secondary compound Cinnamic acid. Cinnamamide is effective as a non-lethal chemical repellent suitable for reducing avian pest damage.
    (E)-Cinnamamide
  • HY-W040149
    Tetramethrin
    		98.20%
    Tetramethrin is a synthetic pyrethroid insecticide for use on a broad spectrum of insect pests.
    Tetramethrin
  • HY-N3097
    Pellitorine
    		99.84%
    Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria.
    Pellitorine