Insecticide

Insecticides refer to any toxic substances used to kill insects, which exert toxic effects on pests through different mechanisms, thereby achieving the purpose of controlling pest populations and protecting crops and human health. Insecticides have both chemical and biological origins and can be classified into organochlorine insecticides, organophosphorus insecticides, carbamate insecticides, and mineral insecticides based on their chemical properties. Insecticides interact with different target and non-target sites, including receptors, enzymes, and many other known and unknown molecules. Most insecticides are neurotoxicants that target the nervous system, but they can also affect other organs and body systems. Insecticides are metabolized through different metabolic pathways and often serve as biomarkers of exposure in the form of their parent compounds or metabolites. The toxicity of insecticides can be acute, subacute, or chronic, depending on the duration of exposure and the dose involved. Therefore, selecting sensitive, accurate, and validated biomarkers of exposure, effects, and susceptibility appears to be a challenging task.
Insecticides are widely used in agriculture, horticulture, forestry, gardening, homes, offices, and other fields^[1]^[2].

References:

[1]. Sparks TC. Insecticide discovery: an evaluation and analysis. Pestic Biochem Physiol. 2013 Sep;107(1):8-17. [Content Brief]

[2]. Gupta R C, et al. Insecticides[M]//Biomarkers in toxicology. Academic Press, 2019: 455-475.

Insecticide Related Products (349):

By Effects:	Inhibitors (27) Activator (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-B1575

Butopyronoxyl
Butopyronoxyl is an insect repellent that can be mainly used to repel mosquitoes.

HY-B1946S

Dimethoate-d₆	Inhibitor
Dimethoate-d₆ is the deuterium labeled Dimethoate. Dimethoate is an organophosphate insecticide and acaricide. Dimethoate is an orally active acetylcholinesterase inhibitor. Dimethoate induces reactive oxygen species (ROS). Dimethoate induces DNA damage and cell apoptosis in vivo. Dimethoate affect immune system in mice.

HY-120425

Ethiprole		≥98.0%
Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity.

HY-W339331

Flubendiamide		99.42%
Flubendiamide is a 1,2-diamide insecticide via action mode of action action by activating the ryanodine receptor.

HY-B2049

Triflumuron		99.0%
Triflumuron is a potent chitin synthesis inhibitor. Triflumuron shows the efficacy in emergence inhibition (EI) against Culex quinquefasciatus and Aedes albopictus, with EI₅₀ values of 5.28 and 1.59 μg/L, respectively. Triflumuron can be used as an insecticide. Triflumuron represents a potential tool for the control of disease vectors in public health.

HY-145297

Flupyrimin		98.14%
Flupyrimin is the antagonist for insect nicotinic acetylcholine receptor (nAChR) that exhibits insecticidal effect by targeting insect nervous system.

HY-W013170

MGK-264		≥98.0%
MgK-264 (N-octylbicycloheptenedicarboximide) is a synergist enhancing the potency of pyrethroid ingredients. MgK-264 has no intrinsic pesticidal qualities itself.

HY-N9496

Piperitone		99.89%
Piperitone is as a powerful repellent and antiappetent agent. Piperitone is very toxic to Cymbopogon schoenanthus (C. schoenanthus) adults, newly laid eggs and to neonate larvae. Insecticidal activity.

HY-18598

Chitinase-IN-1		98.04%
Chitinase-IN-1 is an insecticide that can inhibit the activity of chitinase and N-acetylglucosaminidase. The inhibition percentages for glycosidase and N-acetylglucosaminidase at concentrations of 50 uM and 20 uM are 75% and 67%, respectively.

HY-B1146R

Denatonium benzoate (Standard)
Denatonium (benzoate) (Standard) is the analytical standard of Denatonium (benzoate). This product is intended for research and analytical applications. Denatonium benzoate (THS-839) is the most bitter compound known, commonly used as an aversion agent (bitter agent) to prevent inappropriate ingestion, used in denatured alcohol, antifreeze, nail biting prevention, respirator mask fit testing , animal repellents, liquid soaps and shampoos.

HY-W014566

4-Nitro-3-(trifluoromethyl)phenol		99.91%
4-Nitro-3-(trifluoromethyl)phenol (TFM) is a piscicide that is toxic to lampreys (P. marinus) (LC₅₀ values ??are 1.97-2.11 for cysts, 2.05-2.21 for fry, 1.6-2.45 for juveniles, and 1.6-1.63 for adults, respectively). 4-Nitro-3-(trifluoromethyl)phenol is also toxic to juvenile lake sturgeons (A. fulvescens) less than 100 mm, but is nontoxic to a variety of other fish species. 4-Nitro-3-(trifluoromethyl)phenol (50 μM) dissociates oxidative phosphorylation by 22% and 28% in isolated livers of lampreys and rainbow trout (O. mykiss), respectively. 4-Nitro-3-(trifluoromethyl)phenol can be used to control lamprey larval populations.

HY-117419A

(±)-Lavandulyl acetate		98.0%
(±)-Lavandulyl acetate can be isolated from the oil components of Lavandula angustifolia Mill.

HY-148964

Thiotraniliprole
Thiotraniliprole (HY366) is an ortho formamidobenzamide insecticide that can be used for the synthesis of insecticidal combinations. Thiotraniliprole has potential applications in the prevention of lepidoptera pests, coleoptera pests, ants, and termites.

HY-133204

Chlorfluazuron		98.89%
Chlorfluazuron (IKI-7899) is a benzoylurea insecticide. Chlorfluazuron inhibts insect chitin and disrupts normal exuviation by inducing malformations, thereby preventing and controlling lepidopteran pests.

HY-B0916

Propoxur		99.43%
Propoxur is a reversible, competitive, orally active AChE inhibitor that can cross the blood-brain barrier. Propoxur inhibits AChE activity to induce neurotoxicity, while promoting MMP-2 expression and enhancing tumor cell migration and invasion by inducing intracellular ROS generation and activating the ERK/Nrf2 signaling pathway. On the one hand, Propoxur inhibits AChE, leading to acetylcholine accumulation and causing neurological dysfunction; on the other hand, it promotes Nrf2 nuclear translocation through ROS-dependent ERK1/2 phosphorylation, and upregulates MMP-2 and other invasion-related proteins. Propoxur is also a carbamate insecticide used to combat turf, forestry, and household pests.

HY-119725

Tetradifon		99.78%
Tetradifon is a broad-spectrum organochlorine insecticide and an inhibitor of the mitochondrial oligomycin sensitivity conferring protein (OSCP), which can be used to control a variety of mites. Tetradifon inhibits energy-related activities such as ADP-stimulated respiration, DNP and Mg²⁺-stimulated ATPase, with an IC₅₀ of 4.5-27 nmoL/mg mitochondrial protein. Tetradifon exerts oligomycin-like activity by inhibiting the oxidative phosphorylation process, inducing oxidative stress and interfering with bone metabolism. Tetradifon is currently mainly used in the research of mitochondrial function regulation, bone remodeling mechanism and nephrotoxicity of environmental pollutants.

HY-118541

RH-5849		99.35%
RH-5849 is an orally active agonist for non-steroidal ecdysteroid, which inhibits the larval growth of Plodia inferpuncteila in a dose-dependent manner. RH-5849 exhibits molting hormone activity.

HY-114502

Chrysanthemic acid		99.10%
Chrysanthemic acid (NSC 11779) is an organic compound that is associated with a variety of natural and synthetic insecticides for the prevention of insect-borne diseases, among others.

HY-W052234

4-Fluorophenoxyacetic acid		99.70%
4-Fluorophenoxyacetic acid is a herbicide and plant defense inducer. 4-Fluorophenoxyacetic can inhibit the heading of monocotyledonous weeds and induce their sterility. Additionally, 4-Fluorophenoxyacetic acid can induce the defense mechanism of cereals to suppress pest populations and increase the yield of field crops.

HY-118659

Benzalphthalide		98.04%
Benzalphthalide (3-Benzylidenephthalide), a phthalate compound, is an insecticide.

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