Insecticide

Insecticides refer to any toxic substances used to kill insects, which exert toxic effects on pests through different mechanisms, thereby achieving the purpose of controlling pest populations and protecting crops and human health. Insecticides have both chemical and biological origins and can be classified into organochlorine insecticides, organophosphorus insecticides, carbamate insecticides, and mineral insecticides based on their chemical properties. Insecticides interact with different target and non-target sites, including receptors, enzymes, and many other known and unknown molecules. Most insecticides are neurotoxicants that target the nervous system, but they can also affect other organs and body systems. Insecticides are metabolized through different metabolic pathways and often serve as biomarkers of exposure in the form of their parent compounds or metabolites. The toxicity of insecticides can be acute, subacute, or chronic, depending on the duration of exposure and the dose involved. Therefore, selecting sensitive, accurate, and validated biomarkers of exposure, effects, and susceptibility appears to be a challenging task.
Insecticides are widely used in agriculture, horticulture, forestry, gardening, homes, offices, and other fields^[1]^[2].

References:

[1]. Sparks TC. Insecticide discovery: an evaluation and analysis. Pestic Biochem Physiol. 2013 Sep;107(1):8-17. [Content Brief]

[2]. Gupta R C, et al. Insecticides[M]//Biomarkers in toxicology. Academic Press, 2019: 455-475.

Insecticide Related Products (349):

By Effects:	Inhibitors (27) Activator (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-114899S

Azamethiphos-d₆
Azamethiphos-d₆ is deuterated labeled Azamethiphos (HY-114899). Azamethiphos is an organophosphate insecticide that inhibits AChE. Azamethiphos inhibits sea lice.

HY-123178R

Fenpropathrin (Standard)
Fenpropathrin (Standard) is the analytical standard of Fenpropathrin. This product is intended for research and analytical applications. Fenpropathrin is a synthetic pyrethroid insecticide in agriculture. Fenpropathrin may induces parkinsonian symptoms progressively.

HY-163352

Chitinase-IN-6
Chitinase-IN-6 (Compound 4h) is a potent dual-Chitinase inhibitor, with K_i values of 1.82 and 2.00 μM against OfChtI and OfChi-h, respectively. Chitinase-IN-6 exhibits certain growth inhibition effects against Ostrinia furnacalis. Chitinase-IN-6 is a potential novel insecticide candidate friendly to nontarget organisms.

HY-145297R

Flupyrimin (Standard)
Flupyrimin (Standard) is the analytical standard of Flupyrimin. This product is intended for research and analytical applications. Flupyrimin is the antagonist for insect nicotinic acetylcholine receptor (nAChR) that exhibits insecticidal effect by targeting insect nervous system.

HY-149587

Callosobruchusic acid	Inhibitor
Callosobruchusic acid (R-(-)-Callosobruchusic acid) is an active compound in sex pheromone of the bean pest Callosobruchus chinensis L. Callosobruchusic acid can be used in pest control strategy development.

HY-123693

ML358
ML358 is a first in class, potent, and selective inhibitor of the SKN-1 pathway (IC₅₀=0.24 μM). ML358 sensitizes the model nematode C. elegans to oxidants and anthelmintic. ML358 potentially used as adjuvants to increase the efficacy and useful life of current anthelmintics.

HY-W585834R

Fipronil desulfinyl (Standard)
Fipronil desulfinyl (Standard) is the analytical standard of Fipronil desulfinyl. This product is intended for research and analytical applications. Fipronil desulfinyl is a photodegradation product of the insecticide Fipronil (HY-B0822) and has similar in vivo toxicity to Fipronil but higher environmental pollution.

HY-W040149R

Tetramethrin (Standard)
Tetramethrin (Standard) is the analytical standard of Tetramethrin. This product is intended for research and analytical applications. Tetramethrin is a synthetic pyrethroid insecticide for use on a broad spectrum of insect pests.

HY-B1970

o,p'-DDT
o,p'-DDT (2,4'-DDT) is a chlorinated organic pesticide with estrogenic activity. o,p'-DDT is persistent in the environment, can accumulate in organisms and disrupt the endocrine system. o,p'-DDT is used in agriculture as a pesticide, especially for controlling insect pests. The use of o,p'-DDT has led to toxic effects in organisms, raising widespread concern about its environmental and health effects. o,p'-DDT has also led to research into its long-term effects in ecosystems.

HY-N15090

Milbemycin α10	Inhibitor
Milbemycin α10 is a macrolide antibiotic. Milbemycin α10 has insecticidal effects on agricultural harmful insects, pans, larvae, etc.

HY-112820R

Chlorantraniliprole (Standard)
Chlorantraniliprole (Standard) is the analytical standard of Chlorantraniliprole. This product is intended for research and analytical applications. Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC₅₀s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ～300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC₅₀, 14 μM).

HY-W1007773

Acaricidal agent-1
Acaricidal agent-1 (Compound 34) exhibits acaricide activity, that inhibits P. cuniculi with a LC₅₀ of 0.82 mM (146.6 μg/mL).

HY-119509

Cismethrin
Cismethrin is a pyrethroid insecticide that produces Type I effects on intact nerve.

HY-B1567R

Bromocyclen (Standard)
Bromocyclen (Standard) is the analytical standard of Bromocyclen. This product is intended for research and analytical applications. Bromocyclen is a pesticide found in the muscle tissue of rainbow trout from Danish fisheries and in three species of fish (grill, crucian carp and pike) from the River Stell in northern Germany. High concentrations were detected ranging from 0.09 to 1.23 mg/kg fat.

HY-120253R

Spirotetramat (Standard)
Spirotetramat (Standard) is the analytical standard of Spirotetramat. This product is intended for research and analytical applications. Spirotetramat (BY-108330) is a pesticide, that can be used to control aphids on crops, without significant phytotoxicity.

HY-169565

ETNK-IN-2
ETNK-IN-2 (Compound 8) is an inhibitor of ethanolamine kinase (ETNK) with an IC₅₀ value of ≥ 5 μM, which can be used in research for insecticide development.

HY-119725R

Tetradifon (Standard)
Tetradifon (Standard) is the analytical standard of Tetradifon (HY-119725). This product is intended for research and analytical applications. Tetradifon is a broad-spectrum organochlorine insecticide and an inhibitor of the mitochondrial oligomycin sensitivity conferring protein (OSCP), which can be used to control a variety of mites. Tetradifon inhibits energy-related activities such as ADP-stimulated respiration, DNP and Mg²⁺-stimulated ATPase, with an IC₅₀ of 4.5-27 nmoL/mg mitochondrial protein. Tetradifon exerts oligomycin-like activity by inhibiting the oxidative phosphorylation process, inducing oxidative stress and interfering with bone metabolism. Tetradifon is currently mainly used in the research of mitochondrial function regulation, bone remodeling mechanism and nephrotoxicity of environmental pollutants.

HY-133204R

Chlorfluazuron (Standard)
Chlorfluazuron (Standard) is the analytical standard of Chlorfluazuron. This product is intended for research and analytical applications. Chlorfluazuron (IKI-7899) is a benzoylurea insecticide. Chlorfluazuron inhibts insect chitin and disrupts normal exuviation by inducing malformations, thereby preventing and controlling lepidopteran pests.

HY-119381R

Iodofenphos (Standard)	Inhibitor
Iodofenphos (Standard) is the analytical standard of Iodofenphos. This product is intended for research and analytical applications. Iodofenphos (Jodfenphos) is an insecticide, that can be used as a protectant for stored grains. Iodofenphos is effective against grain pests, such as Sitophilus oryzae, Tribolium castaneum, and larvae of Trogoderma granarium, and has a significant residual toxicity, which could provide good insect control for several months.

HY-167627

Colupulone
Colupulone is a β-acid resin component found in hops (Humulus lupulus) and exhibits antibacterial and anti-larval activity against Culex mosquitoes. Colupulone can be used in studies related to infectious diseases.

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