Insecticide

Insecticides refer to any toxic substances used to kill insects, which exert toxic effects on pests through different mechanisms, thereby achieving the purpose of controlling pest populations and protecting crops and human health. Insecticides have both chemical and biological origins and can be classified into organochlorine insecticides, organophosphorus insecticides, carbamate insecticides, and mineral insecticides based on their chemical properties. Insecticides interact with different target and non-target sites, including receptors, enzymes, and many other known and unknown molecules. Most insecticides are neurotoxicants that target the nervous system, but they can also affect other organs and body systems. Insecticides are metabolized through different metabolic pathways and often serve as biomarkers of exposure in the form of their parent compounds or metabolites. The toxicity of insecticides can be acute, subacute, or chronic, depending on the duration of exposure and the dose involved. Therefore, selecting sensitive, accurate, and validated biomarkers of exposure, effects, and susceptibility appears to be a challenging task.
Insecticides are widely used in agriculture, horticulture, forestry, gardening, homes, offices, and other fields^[1]^[2].

References:

[1]. Sparks TC. Insecticide discovery: an evaluation and analysis. Pestic Biochem Physiol. 2013 Sep;107(1):8-17. [Content Brief]

[2]. Gupta R C, et al. Insecticides[M]//Biomarkers in toxicology. Academic Press, 2019: 455-475.

Insecticide Related Products (326):

By Effects:	Inhibitors (25) Activator (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-169565

ETNK-IN-2
ETNK-IN-2 (Compound 8) is an inhibitor of ethanolamine kinase (ETNK) with an IC₅₀ value of ≥ 5 μM, which can be used in research for insecticide development.

HY-119725R

Tetradifon (Standard)
Tetradifon (Standard) is the analytical standard of Tetradifon (HY-119725). This product is intended for research and analytical applications. Tetradifon is a broad-spectrum organochlorine insecticide and an inhibitor of the mitochondrial oligomycin sensitivity conferring protein (OSCP), which can be used to control a variety of mites. Tetradifon inhibits energy-related activities such as ADP-stimulated respiration, DNP and Mg²⁺-stimulated ATPase, with an IC₅₀ of 4.5-27 nmoL/mg mitochondrial protein. Tetradifon exerts oligomycin-like activity by inhibiting the oxidative phosphorylation process, inducing oxidative stress and interfering with bone metabolism. Tetradifon is currently mainly used in the research of mitochondrial function regulation, bone remodeling mechanism and nephrotoxicity of environmental pollutants.

HY-133204R

Chlorfluazuron (Standard)
Chlorfluazuron (Standard) is the analytical standard of Chlorfluazuron. This product is intended for research and analytical applications. Chlorfluazuron (IKI-7899) is a benzoylurea insecticide. Chlorfluazuron inhibts insect chitin and disrupts normal exuviation by inducing malformations, thereby preventing and controlling lepidopteran pests.

HY-119381R

Iodofenphos (Standard)	Inhibitor
Iodofenphos (Standard) is the analytical standard of Iodofenphos. This product is intended for research and analytical applications. Iodofenphos (Jodfenphos) is an insecticide, that can be used as a protectant for stored grains. Iodofenphos is effective against grain pests, such as Sitophilus oryzae, Tribolium castaneum, and larvae of Trogoderma granarium, and has a significant residual toxicity, which could provide good insect control for several months.

HY-167627

Colupulone
Colupulone is a β-acid resin component found in hops (Humulus lupulus) and exhibits antibacterial and anti-larval activity against Culex mosquitoes. Colupulone can be used in studies related to infectious diseases.

HY-B1881S

Pirimiphos-methyl-d₆
Pirimiphos-methyl-d₆ is the deuterium labeled Pirimiphos-methyl (HY-B1881). Pirimiphos-methyl is an organophosphorus insecticide and acaricide that can inhibit AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains.

HY-120425R

Ethiprole (Standard)
Ethiprole (Standard) is the analytical standard of Ethiprole. This product is intended for research and analytical applications. Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity.

HY-Y0496R

1,4-Dichlorobenzene (Standard)
1,4-Dichlorobenzene (Standard) is the analytical standard of 1,4-Dichlorobenzene. This product is intended for research and analytical applications. 1,4-Dichlorobenzene is used as an intermediate product in the manufacture of pigments, pesticides and disinfectants. 1,4-Dichlorobenzene is also employed as a moth control agent.

HY-155388

ZK-PI-9
ZK-PI-9 inhibits trehalase. ZK-PI-9 inhibits chitinase activity in female pupae. ZK-PI-9 is an insecticide.

HY-141858

Lynamicin B
Lynamicin B is a potential pesticide by acting as a lepidoptera-exclusive chitinase inhibitor with a K_i value of 8.76 μM.

HY-170513

3'-Ethoxy-5,6-dihydrospinosyn J 17-pseudoaglycone
3'-Ethoxy-5,6-dihydrospinosyn J 17-pseudoaglycone is a Spinosyn derivative with potent insecticidal activity. 3'-Ethoxy-5,6-dihydrospinosyn J 17-pseudoaglycone (500mg/L) achieves a 100% mortality rate against Mythimna separata, aphids, and red spiders.

HY-137031

Spinetoram L	Inhibitor
Spinetoram L (XDE-175-L) is a minor component of Spinetoram. Spinetoram is a kind of green and efficient insecticide with a broad range of action against various insects.

HY-147107

OfHex1-IN-2
OfHex1-IN-2 (compound I-79) is a potent β-N-acetylhexosaminidase OfHex1 inhibitor. OfHex1-IN-2 can be used in control of insect.

HY-119863

Barthrin
Barthrin is a pyrethroid insecticide. The toxicity of Barthrin to housefly (Musca domestica L.) at the 50% mortality level is 14 % of that of Barthrin (HY-B1559).

HY-B1161R

Methoprene (Standard)
Methoprene (Standard) is the analytical standard of Methoprene. This product is intended for research and analytical applications. Methoprene, an insect juvenile growth hormone mimic, is a growth-regulating insecticide that manifests its toxicity to target organisms by acting as a juvenile hormone agonist.

HY-W488109

Genite
Genite is a highly effective pesticide with strong insecticidal activity. Genite can effectively control the number of various pests and is widely used in agricultural production. The use of Genite can significantly increase the yield and quality of crops.

HY-B1979

Isochlorthion
Isochlorothion is an organic phosphorus pesticide.

HY-W721291

Penfluron
Penfluron is an insect-growth regulator with chitin-inhibiting activities. Penfluron inhibits the total haemocyte count (THC) of Dysdercus koenigii.

HY-173264

SDH-IN-24
SDH-IN-24 (Compound 51) is an inhibitor of succinate dehydrogenase (SDH). The LC50 against the second-stage juveniles of Bursaphelenchus xylophilus (B. xylophilus) is 6.9 mg/L, and the IC₅₀ for SDH is 15.0 μM. SDH-IN-24 exerts its nematicidal activity by inhibiting the activity of SDH to interfere with the energy metabolism of nematodes. Meanwhile, it inhibits the motility, feeding, and reproduction of nematodes, induces oxidative stress, reduces the protein content of nematodes, and impairs their antioxidant capacity. SDH-IN-24 can be used in the research related to anti-nematode fields.

HY-164342

Netobimin
Netobimin is a dewormer that is effective against naturally acquired gastrointestinal nematodes in cows.

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