2. Signaling Pathways
  3. GPCR/G Protein
  4. G Protein-coupled Receptor Kinase (GRK)
  5. G Protein-coupled Receptor Kinase (GRK) Agonist

G Protein-coupled Receptor Kinase (GRK) Agonist

G Protein-coupled Receptor Kinase (GRK) Agonist (1):

Cat. No. Product Name Effect Purity
  • HY-12976
    DS-1558
    		Agonist
    DS-1558 is an orally active small molecule G protein-coupled receptor 40 agonist. DS-1558 not only increases the glucose-stimulated insulin secretion by glucagon like peptide-1 (GLP-1) but also potentiated the maximum insulinogenic effects of GLP-1 after an intravenous glucose injection in normal Sprague Dawley rats. DS-1558 is promising for research of type 2 diabetes.